A Comparative Double-Blind Study of Tiaprofenic Acid and Aspirin in the Treatment of Muscular Rheumatism,Fibrositis,Sprains and Soft Tissue Injuries in General Practice
Restricted accessResearch articleFirst published online November, 1980
A Comparative Double-Blind Study of Tiaprofenic Acid and Aspirin in the Treatment of Muscular Rheumatism,Fibrositis,Sprains and Soft Tissue Injuries in General Practice
Analgesic and anti-inflammatory properties of tiaprofenic acid 200 mg t.d.s. were compared with those of aspirin 600 mg t.d.s. in 100 patients in general practice suffering from muscular rheumatic pain, fibrositis, sprains and soft tissue injuries.
Tiaprofenic acid was shown to be better than aspirin in relieving pain by clinical assessment although both drugs were equally effective according to patients daily assessment.
It was not possible to demonstrate any anti-inflammatory action by reduction of swelling, but this was only present in 20% of patients initially.
Side-effects, none serious, were similar in both groups.
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References
1.
CampA V (1975) A double-blind trial of phenylbutazone and RU 15060 in rheumatoid arthritis. Scandinavian Journal of Rheumatology4, Supplement 8, 96.
2.
Data on file (1980) Roussel Laboratories (To be published).
3.
DaymondT J (1979) A controlled trial of tiaprofenic acid versus ibuprofen in rheumatoid arthritis. Rheumatology and Rehabilitation18, 257.
4.
PottierJBerlinDRaynaudJ P (1977) Pharmacokinetics of the anti-inflammatory tiaprofenic acid in humans, mice, rats, rabbits and dogs. Journal of Pharmaceutical Sciences66, 1030.
