Twenty post-menopausal women were treated using oestriol vaginal suppositories (Ortho-Gynest®*).
Subjective disturbances such as dyspareunia, pruritis, and kraurosis vulvae showed a good response to the therapy, while the anaplastic activity of the vaginal epithelium to the suppositories was shown by an increase in the vaginal superficial cells which followed the course of treatment. Side-effects were minimal and disappeared following cessation of treatment.
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References
1.
BorgliN EStalandB (1975) Oral treatment of menopausal symptoms with natural oestrogens. Act Obstetrica et Gynecologica Scandinavica Suppl43, 2.
2.
BurchJ C (1975) The effects of long-term estrogen administration to women following hysterectomy. Estrogens in the menopause. Frontiers of Hormone Research3, 203.
3.
DelacroixP (1976) Interêt de l'estriol en practique gynécologique. Revue Française de Gynecologie et d‘ Obstetrique71, 7–9, 513.
4.
TzingounisV (1978) Estriol in the management of the menopause. Journal of the American Medical Association239, 16, 1638.