Fenbufen,a New Non-Steroidal Anti-Inflammatory Agent in Rheumatoid Arthritis,its Efficacy and Toxicity

Abstract

Fenbufen, a new butanoic acid derivative with anti-inflammatory properties, was evaluated in an open-label study. It was found that fenbufen was an effective anti-inflammatory agent with tolerable and acceptable potential side-effects. Its advantages appeared to be its long clinical half-life and relatively mild toxicity and/or allergic response.