We dosed eight normal volunteers with single doses of probenecid alone and with aspirin or ibuprofen. Urinary urate clearance was increased by probenecid. This increase was partially inhibited by aspirin but not by ibuprofen.
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References
1.
FranckW ABrownM M (1976) Ibuprofen in acute polyarticular gout (Letter to the Editor). Arthritis and Rheumatism19, 269.
2.
SchweitzM CNashelD JAlepaF P (1978) Ibuprofen in the treatment of acute gouty arthritis. Journal of the American Medical Association239, 34.
3.
SinclairD SFoxI H (1975) The pharmacology of hypouricemic effect of benzbromarone. Journal of Rheumatology2, 437.
