Two thousand one hundred consecutive administrations of ketamine as an anaesthetic agent are reviewed. On the basis of the experience described, the authors assess that this agent could be used with safety in the average patient presenting for surgery and that it would be likely to suffice as the sole anaesthetic agent in 40% of such cases but would require supplementation by other anaesthetic agents in the remaining 60% of cases. They recommend it as being particularly useful in children submitting to dental surgery as it can be used without sedative premedication and permits of rapid recovery.
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References
1.
ChangTDillW AGlazkoA J (1965) Metabolic disposition of 2-(O-Chlorophenyl)-2-Methyl Amino-Cyclohexanone-HCL (CI 581) in laboratory animals and in man. Federation Proceedings24, 268.
2.
CobenM LChanSin-LamWayW LTrevorA J (1973) Distribution in the brain and metabolism of ketamine in the rat after intravenous administration. Anaesthesiology39, 370.
3.
FallsH FHoyJ ECorssenC (1965) C1-581: An intravenous or intramuscular anaesthetic for office ophthalmic surgery. American Journal of Ophthalmology61, 1093.
4.
KhorramzadehELotfyA O (1973) The use of ketamine in psychiatry. Psychosomatics14, 344.
5.
LotfyA OJahedA K AmirMoarefiP (1970) Anaesthesia with ketamine: Indications, advantages and shortcomings. Anaesthesia and Analgesia49, 969.
6.
RobertsF W (1967) A new intramuscular anaesthetic for small children. Anaesthesia22, 23.
7.
WesselsJ VAllenG WSlogoffS (1973) The effects of nitrous oxide on ketamine anaesthesia. Anaesthesiology39, 282.
