Abstract
In a multicentre evaluation in general practice involving 104 patients, Syndol, a formulation containing paracetamol, codeine phosphate, caffeine, and doxylamine succinate, was shown to be highly effective in treating the organic and psychogenic symptoms of Tension Headache in 81·7% of patients. The evaluation was performed in six widely differing practices in the United Kingdom.
The result confirms the findings of other investigators in South Africa both in the efficacy of the drug and the incidence of Tension Headache in the general population. Drowsiness was the most common side-effect, indicating that the formulation provided sufficient calmative activity, especially in those patients where tension was a major component of their symptoms.
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