Serum levels of kanamicin, bekanamicin, and amikacin were studied, after a single intramuscular dose of each antibiotic, in three groups of diabetic children, with their respective normal controls, paired by age, weight and sex. Lower serum levels were observed with kanamicin and bekanamicin in diabetic children compared to their controls. The difference in low serum levels was less noticeable with amikacin.
Get full access to this article
View all access options for this article.
References
1.
GarrodLPO'GradyF (1968) Antibiotic and chemotherapy. Second Edition. BaltimoreThe Williams and Wilkins company p. 106
2.
Kanamycin (1966) Appraisal after eight years of clinical application. Annals of the New York Academy of Sciences132, 805 Kanendomycin (Bekanamycin) Laboratory and clinical studies. Meijiseikakaisna Tokyo.
3.
Japón KawaguchiH (1972) BBK8 a new semisynthetic aminoglycoside antibiotic. The Journal of Antibiotics25, 695
4.
SimonHJYinEJ (1970) Microbiassay of antimicrobial agents. Applied Microbiology19, 573
5.
UribePATrujilloSHPalacioMde VidalEL (1974) Estudio de sensibilidad in vitro de 802 cepas de varios grupos bacterianos al nuevo aminoglicosido BBK8 (Amikacin). A Folha Médica69 (3), 339
6.
WeinsteinLDaltonAC (1968) Host determinants of response to antimicrobial agents. New England Journal of Medicine279, 467
