An open clinical trial of Locabiotal, in which the antibiotic, fusafungine, is presented in a micronized aerosol was performed in general practice. One hundred and ten patients suffering from upper respiratory infections without associated hyperpyrexia or toxic symptoms were treated for 7 days. There was a marked improvement in the symptoms rated during the first 48 hours. After the full course of treatment 37 patients regarded its effect as excellent and 48 us good.
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References
1.
AbruzziWACohenBM (1968) Etude comparative d'un áerosol de locabiotal pressurisé et d'un placebo dans le traitment des infections des voies respiratoires supérieures (méthode de test double aveugle). Medecine Interne3 (11), 819
2.
ArnsteinHRCookAHLaceyM S (1946) An antibacterial pigment of Fusarium javanicum. Nature157, 333
3.
BagotPGuérinC (1964) Aérosol thérapie en pratique ORL et bronchique: Le locabiotal pressurisé. Vie Medicale, Dec. suppl., 40
4.
BlackW (1972) A propos d'un nouvel antibiotique local en ORL Locabiotal pressurisé. Cahiers d'ORL, June suppl., 87
5.
ChaperonChMaspetiolR (1972) Le traitement local des infections ORL en pédiatrie. Cahiers d'ORL June suppl., 91
6.
Editorial (1974) Antibiotics and respiratory illness. British Medical Journal, Vol 3, 1
Editorial (1975) Antimicrobial treatment of Chronic Bronchitis. Lancet, No. 7905, Vol. I, 505
9.
LarribaudJNarbonneCh (1972) Existe-t-il une Flore Respiratoire ‘Physiologique’ Peut-on la respecter par un Antibiotique Local?Cahiers d'ORL, June suppl., 9
10.
MernsteinJHRogersKD (1974) Steptococcal Pharyngitis: Early treatment and management by nurse practitioners. Journal of the American Medical Association227, 1278
11.
NicougarGR (1972) Etude clinique de l'action d'un nouvel antibiotique anti-inflammatoire dans le traitement local des infections nasosinusiennes. Cahiers d'ORL, June suppl. 77
12.
PiquetJJ (1964) Utilisation en ORL d'un nouvel antibiotique: Le 314S. Vie Médicale, Dec. suppl., 38
13.
PiquetJJHequetBDecroixG (1969) Ińterět de l'utilisation du Locabiotal pressurisé dans la pathologie rhinosinusienne de l'enfant. Gazette Médicale de France, Feb. (No. 6Suppl.), 47
14.
RossPWChistySMKKnoxJDE (1971) Sore throat in children: Its causation and incidence. British Medical Journal2, 624
15.
Study by the East Scotland Faculty, Royal College of General Practitioners and Dept of Bacteriology, The University of Dundee (1975) Acute sore throat—diagnosis and treatment in general practice. Journal of Royal College of General Practitioners25, 126
16.
TherondC (1967) Action thérapeutique d'un antibiotique local anti-inflammatoire dans la lutte contre la surinfection des allergies respiratoires des infantiles. Presse Médicale75 (11), 553
