Amoxycillin ('Amoxil') a new semi-synthetic penicillin was used in the treatment of pneumonia in 30 children. A very satisfactory clinical cure was effected in all cases on a dosage requirement of 125 mg eight hourly for 5-8 days.
There were no side-effects. In view of its regimen of three times daily dosage, proven efficacy and facility of administration with food it should be usefully recommended for routine out-patient/in-patient therapy of childhood pneumonia.
Get full access to this article
View all access options for this article.
References
1.
AcredPHunterPALindaMizenRolinsonGN (1970) α-amino-p-hydroxybenzyl penicillin (BRL 2333), a new broad-spectrum semisynthetic penicillin: in vivo evaluation. Antimicrobial Agents and Chemotherapy (American Society for Microbiology 1971) 416.
2.
BrumfittWPercivalA (1967) Laboratory control of antibiotic therapy in urinary tract infection. New York Academy of Science, 145, 329.
3.
BurgiH (1973) Klinisch-experimentelle Erfahrungen mit Amoxycillin bei chronischer Bronchitis. Chemotherapy 18 Suppl 19
4.
CroydonEAPSutherlandR (1970) α-amino-p-hydroxybenzyl penicillin (BRL 2333), a new semisynthetic penicillin: absorption and excretion in man. Antimicrobial Agents and Chemotherapy (American Society for Microbiology 1971) 427
5.
DeasyPFBourkeM (1974) Trial of Amoxycillin in Paediatrics. Journal of the Irish Medical Association67 (17), 463
6.
HunterPARolinsonGNWittingAD (1973) Comparative Activity of Amoxycillin and Ampicillin in an Experimental Bacterial Infection in Mice. Antimicrobial Agents and Chemotherapy4 285
7.
KhanAA (1966) Review of a year's Paediatric Admissions to the Kenyatta National Hospital, Nairobi, Kenya. Journal of Tropical Medicine69 (1), 69
8.
KhanAA (1972) Who goes whereSelection and Direction Environmental Child Health18 (1), 72
9.
MayJ RIngoldA (1972) Amoxycillin in the treatment of Chronic non-tuberculous bronchial infections. British Journal of Diseases of the Chest66, 185
10.
MayJ R (1972) The Chemotherapy of Chronic Bronchitis. English Universities Press, London
11.
SutherlandRCroydonEAPRolinsonGN (1972) Amoxycillin: a new semi-synthetic penicillin. British Medical Journaliii13
12.
SutherlandRRolinsonGN (1970) α-amino-p-hydroxybenzyl penicillin (BRL 2333), a new semi-synthetic penicillin: in vitro evaluation. Antimicrobial Agents and Chemotherapy (American Society for Microbiology—1971) 411