This paper attempts to establish that affective illnesses are disorders involving the whole body, that mood change is not the primary symptom and that the cause may be a biochemical fault, temporary or permanent, genetically transmitted or acquired.
It is the author's belief that this fault lies in the adenyl cyclase system. The belief is based upon observations made during an extended study of the treatment of affective disorders with clomipramine infusion (O'Flanagan 1973).
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