The side-effects of forty-six patients are studied in this trial, and comparisons are made between female and male groups.
The most persistent and troublesome side-effects are emphasized.
Intravenous treatment was better tolerated than oral therapy.
Valium given in conjunction with Anafranil reduced the severity and incidence of side-effects.
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References
1.
BeaumontGSeldrupJ (1972) Pre-treatment and post-treatment ‘side effects' of clomipramine and their relation to the outcome of treatment. Presented at an Exhibition at the Collegium Internationale Neuro-psychopharmacologicum. Copenhagen, August 1972.
2.
CapstickN (1970) Chlorimipramine (Anafranil) in the treatment of obsessional states. Read at the 7th Congress of the Collegium Internationale Neuro-Psycopharmacologi-cum. Prague, August 1970.
3.
CollinsG H (1972) Anafranil in the treatment of obsessive-compulsive disorders. Obsessional States and their treatment with Anafranil, p 14. Geigy Pharmaceuticals, Macclesfield, Cheshire.
4.
GuyotatJFavre-TissotMMarie-GardineM (1968) A clinical trial with a new anti-depressant (G34,586). Congr's de Psychiatrie et de Neurologie, Dijon (1967) p. 717. Masson, Paris.
5.
JacobidesG M (1968) Clinical study of clomipramine; a new tricyclic anti-depressive. Iatrikai Chron. (Medical Chronicles)8, 814.
6.
JimenezF (1968) A clinical study of Anafranil in depressive, obsessional and schizophrenic patients. Folia Neuropsiquiatrica3, 189.
7.
KuglerJ (1969) Infusion of mono-chloro-imipramine in depressive patients—neurophysiological findings and results of therapy. Arzneimittel-Forschung19, 441.
8.
van Renynghe de VoxvrieG (1968) Anafranil (G34,586) in obsessive neurosis. Acta Neurologica et Psychiatrica Belgica68, 787.