In 88.9% of a group of 18 patients with rheumatoid arthritis participating in an open-label study with fenoprofen calcium (Nalfon), there was observed a mean litre decrease in level of rheumatoid factor as compared to baseline levels.
In follow-up, three months to one year later, a uniform litre increase above the mean level of the study period had occurred. In all cases the titre returned to baseline levels or higher.
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