Red bone marrow extension and increased central bone marrow activity were found in 21 patients with alcoholic liver disease investigated with scintigraphy of the reticuloendothelial system. The patients had no concurrent disease known to alter red bone marrow distribution. The bone marrow extension and the increased pelvic bone marrow activity may be explained as being secondary to a decreased radiocolloid uptake in the liver and could thus be a sign of decreased reticuloendothelial capacity.
AliM. V.NolanJ. P.: Alcohol depression of reticuloendothelial function in the rat. J. Lab. Clin. Med.70 (1967), 295.
2.
AltmeyerP.MunzD. L.HolzmannH.HörG.: Morphological and functional findings of fixed phagocytes in psoriatics. Arch. Dermatol. Res.275 (1983), 95.
3.
CastellD. O.JohnsonR. B.: The 198Au liverscan. An index of portal systemic collateral circulation in chronic liver disease. N. Engl. J. Med.275 (1966), 188.
4.
DatzL.TaylorA.: The clinical use of radionuclide bone marrow imaging. Semin. Nucl. Med.3 (1985), 239.
5.
DibosP. E.JudischJ. M.SpauldingM. B.WagnerH. N.McIntyreP. A.: Scanning the reticuloendothelial system (RES) in hematological diseases. Johns Hopkins Med. J.130 (1972), 68.
6.
DunckerC. M.CarriI.EstorchM.: Radioimmune imaging of bone marrow in patients with suspected bone metastases from primary breast cancer. J. Nucl. Med.9 (1990), 1450.
7.
DrumD. E.BeardJ. O.: Liver scintigraphic features associated with alcoholism. J. Nucl. Med.19 (1978), 154.
8.
FrimanL.: Distribution of the extrahepatic uptake in liver diseases as recorded by scintigraphy. Acta Radiol. Diagnosis22 (1981), 103.
9.
FrimanL.NilssonR.UdénR.: Radionuclide angiography and scintigraphy in hepatocellular carcinoma. Acta Radiol. Diagnosis26 (1985), 577.
10.
FrimanL.PerssonU.UdénR.: Recording of bone marrow activity in liver-spleen (RES) scintigraphy. Acta Radiol. Diagnosis25 (1984), 477.
11.
FrimanL.SöderborgB.: Spleen/liver ratio in RES scintigraphy. Acta Radiol.28 (1987), 439.
12.
FordhamE. W.AliA.: Radionuclide imaging of bone marrow. Semin. Hematol.3 (1981), 222.
13.
GeslienG. E.PinskyF. M.PothR. K.JohnsonM. C.: The sensitivity and specificity of 99mTc-sulfur colloid liver imaging in diffuse hepatocellular disease. Radiology118 (1976), 115.
14.
GroszmannR. J.KravetzD.ParysowO.: Intrahepatic arteriovenous shunting in cirrhosis of the liver. Gastroenterology73 (1977), 201.
15.
HardisonW. G.LeeF. I.: Prognosis in acute liver disease of the alcoholic patient. N. Engl. J. Med.275 (2) (1966), 61.
16.
HorisawaM.GoldsteinG.WaxmanA.ReynoldsT.: The abnormal hepatic scan of chronic liver disease. Its relationship to hepatic hemodynamic and colloid extraction. Gastroenterology71 (1976), 210.
KricunM. E.: Red-yellow marrow conversion. Its effect on the location of some solitary bone lesions. Skeletal Radiol.14 (1985), 10.
19.
LahnborgG.FrimanL.BerghemL.: Reticuloendothelial function in patients with alcoholic liver cirrhosis. Scand. J. Gastroenterol.16 (1981), 481.
20.
LarssonS. M.TuellS. H.MooresK. D.NelpW. B.: Dimensions of the normal adult spleen scan and prediction of spleen weight. J. Nucl. Med.12 (1971), 123.
21.
McCleesE. C.Gedgaudas-McCleesR. C.: Screening for diffuse and focal liver disease. The case for hepatic scintigraphy. J. Clin. Ultrasound12 (1984), 75.
MeekD. R.MillsP. R.GrayH. W.DuncanJ. G.RusselR. I.McKillopJ. H.: A comparison of computed tomography, ultrasound and scintigraphy in the diagnosis of alcoholic liver disease. Br. J. Radiol.57 (1984), 23.
24.
MunzD. L.: Bone marrow scintigraphy. Fundamental principles and clinical results. Nuklearmedizin7 (1984), 251.
25.
NelpW. B.BowerR. E.: The quantitative distribution of the erythron and the RE cell in the bone marrow organ of man. Blood34 (1969), 276.
26.
OseasR. S.SiddiquiA. R.WellmanH. N.BaehnerR. L.: Usefulness of bone marrow imaging in childhood malignancies. J. Pediatr.2 (1982), 206.
27.
ParésA.CaballeriaJ.TorresM.RodésJ.: Histological course of alcoholic hepatitis. J. Hepatol.2 (1986), 33.
28.
RosenthalL.ChartrandR.: Radionuclide imaging of the bone marrow. Can. Med. Assoc. J.100 (1969), 54.
29.
RudbergU.HesserU.UdénR.: Generalized increase of arterial blood flow to the liver observed at visceral radiocolloid angiography. Acta Radiol.30 (1989), 597.
30.
RudbergU.UdénR.AhlbäckS.-O.: Colloid scintigraphy showing red bone marrow extension in patients with prostatic carcinoma. Acta Radiol.33 (1992), 97.
31.
Van DykeD.AngerH. O.: Patterns of marrow hypertrophy and atrophy in man. J. Nucl. Med.6 (1965), 109.
32.
Van DykeD.ShkurkinC.PriceD.YanoY.AngerH. O.: Differences in distribution of erythropoietic and reticuloendothelial marrow in hematological disease. Blood30 (1967), 361.
33.
WasnichR.GloberG.HayashiT.VicherT.YehF.: Simple computer quantitation of spleen-to-liver ratios in the diagnosis of hepatocellular disease. J. Nucl. Med.20 (1979), 149.
34.
WhangK. S.FischM. B.PollycoveM.: Evaluation of hepatic photoscanning with radioactive colloid gold. J. Nucl. Med.6 (1965), 494.
35.
WilsonG. A.KeyesJ. W.Jr: The significance of the liver-spleen uptake ratio in liver scanning. J. Nucl. Med.15 (1974), 593.
