Abstract
The progeria syndrome (Hutchinson-Gilford) is an uncommon disease. A peculiar shape of the proximal radial metaphyseal region caused by an infolding of the cortex was observed on CT in 2 brothers suffering from this disorder, a feature not previously reported. A brief review of the radiologic literature was undertaken. This new observation needs to be further evaluated as it may provide a clinching diagnostic feature of this disease.
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References
1.
Beauregard
S.
Gilchrest
A. B.
: Syndromes of premature aging . Dermatol. Clin.
5 (1987 ), 109 .
2.
De Busk
L. F.
: The Hutchinson-Gilford progeria syndrome . J. Pediatr.
80 (1972 ), 697 .
3.
Gilford
M.
: Progeria — A form of senilism . Practitioner
73 (1904 ), 188 .
4.
Ho
A.
White
S. J.
Rasmussen
E. J.
: Skeletal abnormalities in acrogeria. A progeroid syndrome . Skeletal Radiol.
16 (1987 ), 463 .
5.
Hutchinson
J.
: Congenital absence of hair and mammary gland with atrophic condition of skin and its appendages . Med. Chir. Trans.
69 (1886 ), 473 .
6.
MacLeod
W.
: Progeria . Br. J. Radiol.
80 (1966 ), 224 .
7.
Margolin
R. F.
Steilnbach
L. M.
: Progeria . AJR
103 (1968 ), 173 .
8.
Mitchell
C. E.
Gottman
W. D.
: Progeria. Report of a classic case with review of literature since 1929 . Am. J. Dis. Child.
59 (1940 ), 379 .
9.
Ozonoff
B. M.
Clemett
R. A.
: Progressive osteolysis in progeria . AJR
100 (1967 ), 75 .
10.
Schwarz
E.
: Roentgen findings in progeria . Radiology
79 (1962 ), 411 .