Experimental renal carcinoma was induced by percutaneous injection of VX-2 carcinoma cells into the left kidney in New Zealand white rabbits. Magnetic resonance imaging (MRI) was performed at 0.15 T before and after intravenous injection of 0.3 mmol gadolinium-DTPA (Gd-DTPA) per kg body weight. GdDTPA enhanced the tumors by increasing the signal intensity on T1 weighted images. The enhancement was evident immediately after Gd-DTPA injection, increasing during the observation time of 30 minutes. Histologically the areas of enhancement corresponded well to the viable tumor tissue.
AkinsE. W.FitzsimmonsJ. R.MancusoA. A.AngusL. B.BoucherM.: Improved signal reception using a double loop receiver coil for MR imaging at 0.15 Tesla. J. Comput. Assist. Tomogr.10 (1986), 1083.
2.
BluemmR. G.BloemJ. L.DorrnbosJ.ClausW.TaminianA. H. M.van OosteromA. T.: Gadolinium-DTPA enhanced MR imaging of malignant bone tumors. Initial experience. Radiology157 (P) (1985), 341.
3.
BraschR. C.WeinmannH.-J.WesleyG. E.: Contrastenhanced NMR imaging. Animal studies using Gadolinium-DTPA complex. Amer. J. Roentgenol.142 (1984), 625.
4.
BuonocoreE.HubnerK.KabalkaG.HuangL.MossT.NorleyN.: Targeted MR contrast agents for liver and spleen. Gadolinium labeled liposomas. Radiology157 (P) (1985), 314.
5.
BydderG. M.KingsleyD. P. E.BrownJ.NiendorfH. P.YoungI. R.: MR imaging of meningiomas including studies with and without Gadolinium-DTPA. J. Comput. Assist. Tomogr.9 (1985), 690.
6.
CarrD. H.BrownJ.BydderG. M. et coll.: Gadolinium-DTPA as a contrast agent in MRI. Initial clinical experience in 20 patients. Amer. J. Roentgenol.143 (1984), 215.
7.
ChoykeP. L.FrankJ. A.DwyerA. J. et coll.: MR imaging of renal carcinoma. A comparison of techniques. Radiology161 (P) (1986), 119.
8.
ClaussenC.LaniadoM.KaznerE.SchörnerW.FelixR.: Application of contrast agents in CT and MRI (NMR). Their potential in imaging of brain tumors. Neuroradiology27 (1985), 164.
9.
FelixR.SchörnerW.LaniadoM. et coll.: Brain tumors. MRI imaging with Gadolinium-DTPA. Radiology156 (1985), 681.
10.
FrankJ. A.KnopR. H.SchroderM. et coll.: Gadolinium-DOPA. A new water soluble MR imaging contrast agent. Comparison with Gadolinium-DTPA for organ and pathology localization. Radiology157 (P) (1985), 314.
11.
GrossmanR. I.WolfG.BieryD. et coll.: Gadolinium enhanced nuclear magnetic resonance images of experimental brain abscess. J. Comput. Assist. Tomogr.8 (1984), 204.
12.
HricakH.WilliamsR. D.MoonK. L.Jr et coll.: Nuclear magnetic resonance imaging of the kidney. Renal masses. Radiology147 (1983), 765.
13.
KaudeJ. V.KinardR. E.: Magnetic resonance imaging of renal mass lesions. In: Renal and adrenal tumors. Second edition. Edited by LoehrE.LederL.-D., Springer, Berlin, Heidelberg, New York, Tokyo (in press).
14.
LaniadoM.FieglerW.ClaussenC.SchörnerW.FelixR.: Gd-DTPA in MR imaging of renal tumors. Radiology157 (P) (1985), 276.
15.
PetterssonH.AckermanN.KaudeJ. V. et coll.: Gadolinium-DTPA enhancement of experimental soft tissue carcinoma and hemorrhage in magnetic resonance imaging. Acta Radiol.28 (1987), 75.
16.
RevelD.BraschR. C.PaajanenH. et coll.: Gd-DTPA contrast enhancement and tissue differentiation in MR imaging of experimental breast carcinoma. Radiology158 (1986), 319.
17.
StarkS. S.BradyT. J.WittenbergJ.FerrucciJ. R.Jr: Dynamic spin echo MRI of liver cancer using Gadolinium-DTPA. Animal investigation. Amer. J. Roentgenol.147 (1986), 357.
18.
UngerE. C.LeeJ. K. T.WelchM.: Liposomal Gadolinium-DTPA as a potential MR contrast agent for the liver and spleen. Radiology157 (P) (1985), 314.
19.
WeinmannH.-J.BraschR. C.PressW.-R.WesleyG. E.: Characteristics of Gadolinium-DTPA complex. A potential NMR contrast agent. Amer. J. Roentgenol.142 (1984), 619.
20.
WeinrebJ. C.CohenJ. M.MaravillaK. R.: MR contrast enhancement of human kidneys with gadolinium dimeglumine. Radiology157 (P) (1985), 276.