Sixty-eight patients with coronary heart disease (CHD) i.e. a history of angina of effort and/or previous ‘possible infarction’ were examined inter alia with ECG and cinecardioangiography. A system of scoring was designed which allowed a semiquantitative estimate of the left ventricular asynergy from cinecardioangiography—the left ventricular motion score (LVMS). The LVMS was associated with the presence of a previous myocardial infarction (MI), as indicated by the history and ECG findings. The ECG changes specific for a previous MI were associated with high LVMS values and unspecific or absent ECG changes with low LVMS values. Decision thresholds for ECG changes and asynergy in diagnosing a previous MI were evaluated by means of a ROC analysis. The accuracy of ECG in detecting a previous MI was slightly higher when asynergy indicated a ‘true MI’ than when autopsy result did so in a comparable group. Therefore the accuracy of asynergy (LVMS ≥ 1) in detecting a previous MI or myocardial fibrosis in patients with CHD should be at least comparable with that of autopsy (scar >1 cm).
AustenW. G.EdwardsJ. E., Frye R. L. et coll.: A reporting system on patients evaluated for coronary artery disease. Report of the ad hoc committee for grading of coronary artery disease, council on cardiovascular surgery. American Heart Association. Circulation51 (1975), 4.
2.
BackmanC.JacobssonK.-A.LinderholmH.OstermanG.: Acute myocardial infarction during a one year follow-up study after coronary bypass surgery. (In manuscript.).
3.
BjörkL.CullhedI.HallénA.: Cineangiographic studies of the left ventricle in patients with angina pectoris. Circulation36 (1967), 868.
4.
BjurulfP.GarlindT.SternbyN. H.: On epidemiologic methods for recording ischemic heart disease. Acta Med. Scand. (1967) Suppl. No. 474.
5.
BlackburnH.KeysA.SimonssonE.RautaharjuP.PunsarS.: The electrocardiogram in population studies. A classification system. Circulation21 (1960), 1160.
6.
BrandtP. W.PartridgeJ. B.WattieW. J.: Coronary arteriography. Method of presentation of the arteriogram report and a scoring system. Clin. Radiol.28 (1977), 361.
7.
ChatterjeeK.SwanH. J. C.ParmleyW. W.SustaitaH.MatloffJ.: Depression of left ventricular function due to acute myocardial ischemia and its reversal after aortocoronary saphenous-vein bypass. New Engl. J. Med.286 (1972), 1117.
8.
CohnP. F.GorlinR.AdamsD. F.ChahineR. A.VokonasP. S.HermanM.: A comparison of biplane and single plane left ventriculograms in patients with coronary artery disease. Amer. J. Cardiol.33 (1974), 1.
9.
DahlbergG.: Statistical methods for medical and biological students. Georg Allen and Unwin, London1949.
10.
GarretH. E.: Statistics in psychology and education. Fifth edition. Longmans, Green and Co., New York1969.
HermanM. V.GorlinR.: Implications of left ventricular asynergy. Amer. J. Cardiol.23 (1969), 538.
13.
HoranL. G.FlowersN. C.JohnsonJ. C.: Significance of the diagnostic Q wave of myocardial infarction. Circulation43 (1971), 428.
14.
HutchinsG. M.BulkleyB. H.RidolfiR. L.GriffithS. C.LohrF. T.PiasioM. A.: Correlation of coronary arteriograms and left ventriculograms with postmortem studies. Circulation56 (1977), 32.
15.
IdekerR. E.BeharV. S., Wagner G. S. et coll.: Evaluation of asynergy as an indicator of myocardial fibrosis. Circulation57 (1978), 715.
16.
KaplanB. M.BerksonD. M.: Serial electrocardiograms after myocardial infarction. Ann. Intern. Med.60 (1964), 430.
17.
KerberR. E.MarcusM. L.ErhardtG.WilsonR.ArboudF. M.: Correlations between echocardiographically demonstrated segmental dyskinesis and regional myocardial perfusion. Circulation52 (1975), 1097.
18.
KjellbergS. R.LönrothH.RudheU.: The effect of various factors on the roentgenological determinations of the cardiac volume. Acta radiol.35 (1951), 413.
19.
LevineJ. A.BechtelD. J., Cohn P. F. et coll.: Ventricular function before and after direct revascularization surgery. A proposal for an index of vascularization to correlate angiographic and ventriculographic findings. Circulation51 (1975), 1071.
20.
LinderholmH.StrandellT.: Heart volume in the prone and erect positions in certain heart cases. Acta Med. Scand.162 (1958), 247.
21.
MetzC. E.: Basic principles of ROC analysis. Sem. Nucl. Med.8 (1978), 283.
22.
RautaharjuP. M.BlackburnH. W.WarrenJ. W.: The concepts of sensitivity, specificity and accuracy in evaluation of electrocardiographic, vectorcardiographic and polarographic criteria. J. Electrocardiol.9 (1976), 275.
23.
RingqvistI.FisherL. D., Mock M. et coll.: Prognostic value of angiographic indices of coronary artery disease from the coronary artery surgery study (CASS). J. Clin. Invest.71 (1983), 1854.
24.
RoseG.: The diagnosis of ischemic heart strain and intermittent claudication in field service. Bull. WHO27 (1962), 645.
25.
RoseG.: Predicting coronary heart disease from minor symptoms and electrocardiographic findings. Brit. J. Prev. Soc. Med.25 (1971), 94.
26.
RoseG.BlackburnH.: Cardiovascular survey methods. World Health Organization, Geneva1968.
27.
SavageR. M.WagnerG. S.IdekerR. E.PodolskyS. A.HackelD. B.: Correlation of postmortem anatomic findings with electrocardiographic changes in patients with myocardial infarction. Circulation55 (1977), 279.
28.
SnedecorG. W.: Statistical methods. Fifth edition. Iowa State University Press, Ames, Iowa1961.
29.
StrandellT.: Heart rate and work load at maximal working intensity in old men. Acta Med. Scand.176 (1964), 301.
