A clinical comparison of ioxaglate and diatrizoate with regard to the cardiovascular effects following selective pulmonary angiography was performed in 20 patients with normal pulmonary arterial pressure. Ioxaglate produced a significantly less marked effect on systemic blood pressure (p<0.001), pulmonary arterial pressure (p<0.001), and heart rate (p<0.05–0.01), as compared with diatrizoate.
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References
1.
AgarwalJ. B.BaileE. M.PalmerW. H.: Reflex systemic hypotension due to hypertonic solution in pulmonary circulation. J. App. Physiol.27 (1969), 251.
2.
AlménT.AspelinP.: Cardiovascular effects of ionic monomeric, ionic dimeric and non-ionic contrast media. Effects in animals on myocardial contractile force, pulmonary and aortic blood pressure and aortic endothelium. Invest. Radiol.10 (1975), 557.
3.
AlménT.AspelinP.LevinB.: Effect of ionic and non-ionic contrast medium on aortic and pulmonary arterial pressure. An angiocardiographic study in rabbits. Invest. Radiol.10 (1975), 519.
4.
AspelinP.: Effects of ionic and non-ionic contrast media on morphology of human erythrocytes. Acta radiol. Diagnosis19 (1978), 675.
5.
AspelinP.: Effect of ionic and non-ionic contrast media on red cell deformability in vitro. Acta radiol. Diagnosis20 (1979), 1.
6.
BinetL.BursteinM.: Sur les effets cardiovasculaires du sérum salé hypertonique. C. R. Soc. Biol. (Paris)147 (1953), 1997.
7.
BrownR.RahimtoolA. S. M.DavisG. B.SwanH. G. C.: The effect of angiocardiographic contrast medium on circulatory dynamic in man. Circulation31 (1965), 234.
8.
CumberlandD. C.: Hexabrix. A new contrast medium in angiocardiography. Brit. Heart J.45 (1981), 698.
9.
DimondE. G.GonlubolF.: Death following angiocardiography. Report of two cases after administration of diodrast and neoiopax respectively. New Engl, J. Med.249 (1953), 1029.
10.
DotterC. T.JacksonF. S.: Death following angiocardiography. Radiology54 (1950), 527.
11.
EliakimM. D.RosenbergS. Z.BraunK.: Effect of hypertonic saline on the pulmonary and systemic pressures. Circulat. Res.6 (1958), 357.
12.
EriksonU.HemmingssonA.: Experiences with ioxaglate (Hexabrix) in cardioangiography and peripheral angiography. Acta radiol. Diagnosis22 (1981), 673.
13.
FisherH. W.: Hemodynamic reactins to angiographic media. A survey and commentary. Radiology91 (1968), 66.
14.
GonzalesL. L.StiertitzD.: Cardiovascular responses to injection of contrast medium into proximal aorta. Radiology8 (1966), 1070.
15.
GraingerR. G.: Osmolality of intravascular contrast media. Brit. J. Radiol.53 (1980), 739.
16.
HolmM.PraestholmJ.: Ioxaglate, a new low osmolar contrast medium used in femoral angiography. Brit. J. Radiol.52 (1979), 169.
17.
InglesbyT. V.RaiznerA. E.HanleyH. G.SkinnerN. S.: Cardiovascular reflexes induced by selectively altering pulmonary arterial osmolality. Amer. J. Physiol.222 (1972), 302.
18.
KumazakiT.: Ioxaglate versus diatrizoate in selective pulmonary angiography. I. Subjective reactions. Acta radiol. Diagnosis26 (1985), 467.
19.
KumazakiT.HosoiS.SugawaraK.HondaK.: Bronchial and intercostal angiography with ioxaglate and diatrizoate in man. A comparative investigation. Acta radiol. Diagnosis25 (1984), 49.
20.
LesterE. R.: Angiocardiography. Proc. roy Soc. Med.54 (1961), 469.
21.
LindgrenP.: Hemodynamic responses to contrast media. Invest. Radiol.5 (1970), 424.
22.
MevesM.KieferH.: Klinische Erfahrungen mit Ioxaglat. Einem neuen Kontrastmittel für die Angiographie. RÖFO133 (1980), 657.
23.
MillsS. R.JacksonD. C.OlderR. A.HeastonD. K.MooreA. V.: The incidence, etiologies, and avoidance of complications of pulmonary angiography in a large series. Radiology136 (1980), 295.
24.
MåreK.ViolanteM.: Pulmonary edema induced by high intravenous doses of diatrizoate in the rat. Acta radiol. Diagnosis24 (1983), 419.
25.
NymanU.NilssonP.WestergrenA.: Pain and hemodynamic effect in aortofemoral angiography. Clinical comparison of iohexol, ioxaglate and metrizamide. Acta radiol. Diagnosis23 (1982), 389.
26.
ReadR.MeyerM.: The role of red cell agglutination in arteriographic complications. Surg. Forum10 (1959), 472.
ReadR.VickJ. A.MeyerM. W.: Influence of dextran infusion on the pulmonary hypertensive effect of concentrated saline. Circ. Res.9 (1961), 1240.
29.
RoweG. G.HustonJ. H.TuchmanH.MaxwellG. M.WeinsteinA. B.CrumptonC. W.: The physiologic effect of contrast media used for angiocardiography. Circulation13 (1956), 896.
30.
SniderG. L.FerrisE.GaenslerE. A. et coll.: Primary pulmonary hypertension. A fatality during pulmonary angiography. Chest64 (1973), 628.
31.
TillmannU.AdlerR.FuchsW. A.: Pain in peripheral arteriography. A comparison of a low osmolality contrast medium with a conventional compound. Brit. J. Radiol.52 (1979), 102.
32.
ThompsonW. M.MillsS. R.BatesM.HedlundL.RommelJ.: Pulmonary angiography with iopamidol and renografin 76 in normal and pulmonary hypertensive dogs. Acta radiol. Diagnosis24 (1983), 425.
33.
Van WaesP. F.: New low osmolality water-soluble contrast compounds in selective arteriography of the peripheral limbs. A comparative study. Diag. Imaging48 (1979), 209.
34.
WatsonH.: Severe pulmonary hypertensive episodes following angiocardiography with sodium metrizoate. LancetII (1964), 732.
35.
WellsR.Schmid-SchönbeinH.: Red cell deformation and fluidity of concentrated cell suspensions. J. appl. Physiol.27 (1969), 213.
36.
ZachrissonB. F.JohanssonR.BjörkL.: Two new contrast media in peripheral arteriography. A double blind study in patients with arterial insufficiency in the legs. RÖFO132 (1980), 208.
