Two cases of zolpidem tolerance and dependence are reported. The literature is reviewed for other reported cases, and the potential for abuse of zolpidem is discussed.
Perrault G., Morel E., Sanger D.J., Zivkovic B. (1992) Lack of tolerance and physical dependence upon repeated treatment with the novel hypnotic zolpidem. J Pharmac Exp Ther263: 298-303
9.
Schoch P., Moreau J.L., Martin J.R., Haefely W.E. (1993) Aspects of benzodiazepine receptor structure and function with relevance to drug tolerance and dependence. Biochem Soc Symp59:121-134
10.
Sullivan G., McBride A.J., Clee W.B. (1995) Zopiclone abuse in south Wales: three case reports . Hum Psychopharmac10: 351-352
11.
Thome J., Ruchsow M., Rosler M., Becker T. (1995) Zolpidem-Abhangigkeit und Depression in Senium . Psychiat Prax22:165-166
12.
Wheatley D. (1992) Prescribing short-acting hypnosedatives. Current recommendations from a safety perspective. Drug Safety7: 106-115