5-HT receptors,genes and antipsychotic mechanisms

Arranz M. , Collier D. , Sodhi M. , Ball D. , Roberts G. , Price J. , Sham P. , Kerwin R. (1995) Association between clozapine response and allelic variation in 5-HT2A receptor genes. Lancet 346: 281-282

Bakshi V.P. , Geyer M.A. (1995) Antagonism of phencyclidine induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine. Psychopharmacology 122: 198-201

Laux G. , Kleiser E. , Schröder H.G. , Dittman V. , Unterweger B. , Schubert H. , König P. , Schöny H.W. , Bunse J. , Beckmann H. (1990) A double-blind multicentre study comparing remoxipride, two and three times daily, with haloperidol in schizophrenia. Acta Psychiat Scand 82 (Suppl. 358): 125-129

Nimgaonkar V.L. , Zhang X.R. , Brar J.S. , Deleo M. , Ganguli R. (1996) 5-HT2 receptor gene locus: association with schizophrenia or treatment response not detected. Psychiat Genet 6: 23-28

Nutt D.J. (1994) Putting the 'A' in atypical: does α2-adrenoceptor antagonism account for the therapeutic advantage of new antipsychotics? J Psychopharmac 8:193-195

Reynolds G.P. (1995) Neurotransmitter systems in schizophrenia. Int Rev Neurobiol 38: 305-339

Reynolds G.P. (1996) The importance of dopamine D4 receptors in the action and development of antipsychotic agents. Drugs 51: 7-11

Sodhi M.S. , Arranz M.J. , Ball D. , Sham P. , Curtis D. , Roberts G.W. , Price J. , Collier D.A. , Kerwin R.W. (1995) Association between clozapine response and allelic variation in the 5-HT2C receptor gene. Neuroreport 7:169-172

Soni S.D. , Malik A. , Schiff A.A. (1990) Sulpiride in negative schizophrenia: a placebo-controlled double-blind assessment. Hum Psychopharmac 5: 233-238

Tecott L.H. , Sun L.M. , Akana S.F. , Struch A.M. , Lowenstein D.H. , Dallman M.F. , Julius D. (1995) Eating disorder and epilepsy in mice lacking 5-HT 2C serotonin receptors. Nature 374: 542-546

Williams J. , Sparlock G. , McGuffin P. , Mallet J. , Nothen M.M. , Gill M. , Aschauer H. , Nylander P.O. , Macciarfi F. , Owen M.J. (1996) Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. Lancet 347: 1294-1296