Adenosinergic psychopharmaceuticals: just an extra cup of coffee?

Arch J R S , Newsholme E.A. 1978 Activities and some properties of 5'-nucleotidase, adenosine kinase and adenosine deaminase in tissues from vertebrates and invertebrates in relation to the control of concentration and the physiological role of adenosine. Biochem J 174: 965-977

Boulenger J.P. , Uhde T.W. , Wolff E.A. , Post R.M. 1984 Increased sensitivity to caffeine in patients with panic disorders. Preliminary evidence. Arch Gen Psychiat 41: 1067-1071

Bowmer C.J. , Yates M.S. 1989 Therapeutic potential for new selective adenosine receptor ligands and metabolism inhibitors. TiPS 10: 339-342

Bridges A.J. , Moos H.W. , Szotek D.L. , Trivedi B.K. , Bristol J.A. , Heffner T.G. , Bruns R.F. , Downs D.A. 1987 N6-(2,2-diphenylethyl)-adenosine, a novel adenosine receptor agonist with antipsychotic-like activity. J Med Chem 30: 1709-1711

Bruns R.F. , Daly J.W. , Snyder S.H. 1980 Adenosine receptors in brain membranes: binding of N6-cyclohexyl[3H]adenosine and 1,3-diethyl-8-[3H]phenylxanthine. Proc Natl Acad Sci USA 77: 5547-5551

Casas M. , Ferre S. , Guix T. Jane F 1988 Theophylline reverses haloperidol-induced catalepsy in the rat. Biol Psychiat 24: 642-648

Conners C.K. 1979 The acute effects of caffeine on evoked response, vigilance and activity levels of hyperkinetic children. J Abnorm Child Psychol 7: 145-151

Coffey C.E. , Weiner R.D. Hinkle P E, Cress M. , Daughtry G. , Wilson W.H. 1987 Augmentation of ECT seizures with caffeine. Biol Psychiat 22: 647-649

Daly J.W. , Padgett W. , Shamim M.T. 1986 Analogues of caffeine and theophylline: effect of structural alerations on affinity at adenosine receptors. J Med Chem 28: 487-492

DeFreitas B. , Schwartz G. 1979 Effects of caffeine in chronic psychiatric patients . Am J Psychiat 136: 1337-1338

Deckert J. , Bisserbe J.C. , Kline E. , Marangos P.J. 1988 Adenosine uptake sites in brain: regional distribution of putative subtypes in relationship to adenosine A 1 receptors. J Neurosci 8: 2338-2349

Deckert J. , Morgan P.F. , Marangos P.J. 1988. Adenosine uptake heterogeneity in the mammalian CNS? Uptake inhibitors as probes and potential neuropharmaceuticals. Life Sci 42: 1331-1345

Deckert J. , Gleiter C.H. 1989 Adenosinergic psychopharmaceuticals. TiPS , 10: 99-100

Deckert J. , Verma A. , Marangos P.J. 1989 [3H]DIpyridamole([3H]DPR) and [3H]nitrobenzylthioinosine ([3H]NBI) binding in human brain and erythrocytes. J Neurochem (Supplement 1 ) 74

Dragunow M. , Raull R L M 1988 Neuroprotective effects of adenosine. TiPS 9: 193-194

Fastbom J. , Pazos A. , Probst A. , Palacios J.M. 1987 Adenosine A1 receptors in the human brain: a quantitative autoradiographic study. Neuroscience 22: 827-839

Ferkany J.M. , Valentine H. Stone G. , Williams M. 1986 Adenosine A1 receptors in mammalian brain: species differences in their interactions with agonists and antagonists. Drug Develop Res 9: 85-93

Fink M. 1987 New technology in convulsive therapy: a challenge in training . Am J Psychiat 144: 1195-1198

Fredholm B.B. , Dunwiddie T.V. 1988 How does adenosine inhibit transmitter release? TiPS, 9: 130-135

Gerlach E. , Becker B.F. 1987 Topics and perspectives in adenosine research. Springer, Berlin

Ghai G. , Francis J.E. , Williams M. , Dotson R.A. , Hopkins M.F. , Cote D.T. , Goodman F.R. , Zimmerman M.B. 1987 Pharmacological characterization of CGS 15943 A: a novel non-xanthine antagonist. J Pharmacol Exp Ther 242: 784-790

Gleiter C.H. , Deckert J. , Nutt D.J. 1988 Changes in caffeine seizure threshold after electroconvulsive shock. Psychopharmacology 95: 544-545

Gleiter C.H. , Deckert J. Nutt D J, Marangos P.J. 1989 Electroconvulsive shock (ECS) and the adenosine neuromodulatory system. J Neurochem 52: 641-646

Goodman Gilman A , Goodman L S , Rall T W , Murad F (eds) 1985 The pharmacological basis of therapeutics. Macmillan, New York

Goodman R.R. , Snyder S.H. 1982 Autoradiographic localization of adenosine receptors in rat brain using [3H]cyclohexyladenosine. J Neurosci 2: 1230-1241

Greden J.F. 1981 Caffeinism and caffeine withdrawal. In: Lowinson H J , Ruiz P (eds) Substance abuse. Clinical problems and perspectives. Williams and Wilkins, Baltimore, pp 274-286

Hagberg H. , Andersson P. , Lazarewicz J. , Jacobson I. , Butcher S. , Sandberg M. 1987 Extracellular adenosine, inosine, hypoxanthine and xanthine in relation to tissue nucleotides and purines in rat striatum during ischemia . J Neurochem 49: 227-231

Hare R.B. 1968 Sleep in the elderly. Can Med Assoc J 98: 176

Hindmarch I. , Subhan Z. 1985 A preliminary investigation of Albert 285', HWA 285 on psychomotor performance, mood and memory. Drug Develop Res 5: 379-385

Ho A.D. , Ganeshaguru K. 1988 Enzymes of purine metabolism in lymphoid neoplasms, clinical relevance for treatment with enzyme inhibitors. Klin Wochenschr 66: 467-474

Hoppenbrouwers M.L. , VanDenBussche G. 1989 Mioflazine. a nucleoside transport inhibitor is effective as a sleep promotor in humans. In: Wauquier A. Dugovic C , Radulovacki M (eds) Slow wave sleep: physiological, pathophysiological and functional aspects. Raven Press , New York, pp 301-309.

Jacobson K.A. , Kirk K.L. , Padgett W.L. , Daly J.W. 1986 A functionalized congener approach to adenosine receptor antagonists: amino acid conjugates of 1,3-dipropylxanthine. J Pharmacol Exp Ther 29: 126-133

Jarvis M. , Schulz R. , Hutchinson A.J. , Do U.H. , Sills M.A. , Williams M. 1989 [3H]CGS 21 860, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain J Pharmacol Exp Ther 251: 888-893

Kolossa N. , Pfleger K. , Rummel W. 1970 Specificity of adenosine uptake into the heart and inhibition by dipyridamole. Europ J Pharmacol 9: 265-268

Lee K.S. , Reddington M. 1986 1,3-Dipropyl-8-cyclopentylxanthine (DPCPX) inhibition of [3H]N-ethylcarboxamidoadenosine (NECA) allows the visualization of putative non-A1 adenosine receptors. Brain Res 368: 394-389

Lee K.S. , Schubert P. , Reddington M. Kreutzberg G W 1986 The distribution of adenosine A1 receptors and 5'nucleotidase in the hippocampal formation of several mammalian species. J Comp Neurol 246: 427-434

Lieberman H.R. , Wurtman R.J. , Emde G.G. , Roberts C. , Coviella I.L. 1987 The effects of low doses of caffeine on human performance and mood. Psychopharmacology 92: 99-109

Nagy J.I. , La Bella L.A. , Buss M. , Daddona P.E. 1984 Immunohistochemistry of adenosine deaminase: implications for adenosine neurotransmission. Science 224: 166-168

Newby A.C. 1984 Adenosine and the concept of retaliatory metabolites . TiBS 9: 42-44

Paul B. , Chen M.F. , Paterson A R P 1975 Inhibitors of nucleoside transport. A structure-activity study using human erythrocytes. J Med Chem 18: 968-972

Pellow S. , Chopin P. , File S.E. , Briley M. 1985 Validation of open-closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Meth 14: 149-167

Phillis J W, Edstrom J P, Kostopoulos G.K. , Kirkpatrick J.R. 1979 Effects of adenosine and adenine nucleotides on synaptic transmission in the cerebral cortex. Can J Physiol Pharmacol 57: 1289-1312

Philips E. , Newsholme E.A. 1979 Maximum activities, properties and distribution of 5'-nucleotidase, adenosine kinase and adenosine deaminase in rat and human brain. J Neurochem 33: 553-558

Radulovacki M. , Virus R.M. , Djuricic-Nedelson M. , Green R.D. 1984 Adenosine analogs and sleep in rats. J Pharmacol Exp Ther 228: 268-274

Reimann H.A. 1967 Caffeinism. J Am Med Assoc 202: 1105-1106

Schubert P. , Lee K. , West M. , Deadwyler S. , Lynch G. 1976 Stimulation-dependent release of [3H]-adenosine derivatives from central axon terminals to target neurons. Nature 260: 541-542

Silinsky E.M. , Hubbard J.I. 1973 Release of ATP from rat motor nerve terminals. Nature 243: 404-405

Slapke J. , Hummel S. , Wilke A. , Wenz W. , Meister M. , Förster R. , Weisner B. , Nussbücker B. 1988 Asthmatherapie mit Theophyllinpräparaten. Z Erkr Atmungsorgane 170: 32-48

Stone G.A. , Jarvis M.F. , Sillis M.A. , Weeks B. , Snowhill E.W. , Williams M. 1988 Species differences in high affinity adenosine A2 receptor binding sites in striatal membranes from mammalian brain. Drug Develop Res 15: 31-46

Van Calker D , Müller M. , Hamprecht B. 1979 Adenosine regulates, via two different types of receptors the accumulation of cyclicAMP in cultured brain cells. J Neurochem 33: 999-1005

Williams M. 1987 Purinergic receptors and central nervous system function . In: Meltzer H Y (ed) Psychopharmacology: the third generation of progress. Raven Press, New York, pp 284-301

Williams M. , Jarvis M.F. 1988 Adenosine antagonists as potential therapeutic agents . Pharmacol Biochem Behav 29: 433-441

Winsky L. , Harvey J.A. 1987 Effects of N6-(L-phenylisopropyl)adenosine, caffeine, theophylline and rolipram on the acquisition of conditioned responses in the rabbit. J Pharmacol Exp Ther 241: 223-229

Wu P.H. , Phillis J.W. 1984 Commentary: uptake by central nervous tissue as a mechanism for the regulation of extracellular adenosine concentrations. Neurochem Inter 613-632