Peptide-dopamine interactions in the central nervous system: implications for neuropsychiatric disorders

Algeri S. , Calderini G. , Consolzaione A. , Garattim S. 1977 The effect of methionine-enkephalin and D-alanine methionine-enkephalinamide on the concentration of dopamine metabolites in rat striatum European Journal of Pharmacology 45: 207-209

Allen J.M. , Cross A.J. , Yeats J.C. , Ghatei M.A. , McGregor G.P. , Pay S. , Close S.P. , Marriott A.S. , Tyers M.B. , Crow T.J. , Bloom S.R. 1986 Neuropeptides and dopamine m the marmoset. Effect of treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): an animal model for Parkinson's disease? Brain 109: 143-157

Andrews J.S. , Saghal A. 1983 The effects of thyrotropin-releasing hormone, metabolites and analogues on locomotor activity in rats Peptides 7: 97-109

Arai H. , Emson P.C. 1986 Regional distribution of neuropeptide K and other tachykinins (neurokinin A, neurokinin B and substance P) in rat central nervous system Brain Research 399: 240-249

Arai H. , Emson P.C. , Carrasco L.H. 1987 Huntington's disease: changes in tachykinin content in postmortem brains Annals of Neurology 22: 587-594

Arneric S.P. , Reis D.J. 1986 Somatostatin and cholecystokinin octapeptide differentially modulate the release of [3H]acetylcholine from caudate nucleus but not cerebral cortex: role of dopamine receptor activation Brain Research 374: 153-161

Aronin N. , Cooper P.E. , Lorenz L.J. , Bird E.D. , Sagar S. , Leeman S.E. , Martin J.B. 1983 Somatostatin is increased in the basal ganglia in Huntington's disease Annals of Neurology 13: 519-526

Bannon M.J. , Elliott P.J. , Bunney E.B. 1987 Striatal tachykinin biosynthesis: regulation of mRNA and peptide levels by dopamine agonists and antagonists Molecular Brain Research 3: 31-37

Bannon M.J. , Elliott P.J. , Alpert J.E. , Goedert M. , Iversen S.D. , Iversen L.L. 1983 Role of endogenous substance P in stress-induced activation of mesocortical dopamine neurons Nature 306: 791-792

Bannon M.J. , Lee J-M. , Giraud P. , Young A. , Affolter H-U. , Bonner T.I. 1986 Dopamine antagonist haloperidol decreases substance P, substance K, and preprotachykinin mRNAs in rat striatonigral neurons Journal of Biological Chemistry 261: 6640-6642

Baruch P. , Artaud F. , Godeheu G. , Barbeito L. , Glowinski J. , Cheramy A. 1988 Substance P and neurokinin A regulate by different mechanisms dopamine release from dendrites and nerve terminals of the nigrostriatal dopaminergic neurons Neuroscience 25: 889-898

Beal M.F. , Martin J.B. 1984a The effect of somatostatin on striatal catecholamines Neuroscience Letters 44: 271-276

Beal M.F. , Martin J.B. 1984b Effects of neuroleptic drugs on brain somatostatin-like-immunoreactivity Neuroscience Letters 47: 125-130

Beal M.F. , Martin J.P. 1984c Depletion of striatal somatostatin by local cysteamine injection Brain Reseach 308: 319-324

Beal M.F. , Kowall N.W. , Ellison D.W. , Mazurek M.F. , Swartz K.J. , Martin J.B. 1986 Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid Nature 321: 168-171

Bean A.J. , Baldy W.J. , Martin G.E. 1985 Chronic proglumide increases [3H]spiperone binding in the rat brain European Journal of Pharmacology 117: 97-101

Beresford I J M , Hall M.D. , Clark C.R. , Hill R.G. , Hughes J. , Sirinathsinghji D J S 1987 Striatal lesions and transplants demonstrate that cholecystokinin receptors are localized on intrinsic striatal neurones: a quantitative autoradiographic study Neuropeptides 10: 109-136

Bissette G. , Nemeroff C.B. , MacKay A V P 1986 neuropeptides and schizophrenia In: Emson P C, Rossor M N, Tohyama M eds Progress in brain research. Vol. 66. Peptides and neurological disease. Amsterdam : Elsevier, pp. 161-174

Bissette G. , Nemeroff C.B. , Decker M.W. , Kizer J.S. , Agid Y. , Javoy-Agid F. 1985 Alterations in regional brain concentrations of neurotensin and bombesin in Parkinson's disease Annals of Neurology 17: 324-328

Blaha C.D. , Phillips A.G. , Lane R.F. 1987 Reversal by cholecystokinin of apomorphine-induced inhibition of dopamine release in the nucleus accumbens of the rat Regulatory Peptides 17: 301-310

Bloom F. , Segal D. , Ling N. , Guillemin R. 1976 Endorphins: profound behavioral effects in rats suggest new etiological factors in mental illness Science 194: 630-632

Blumstein L.K. , Crawley J.N. , Davis L.G. , Baldino F. Jr 1987 Neuropeptide modulation of apomorphine-induced stereotyped behaviour Brain Research 404: 293-300

Bock M.G. , DiPardo R.M. , Evands B.E. , Rittle K.E. , Whitter W.L. , Veber D.F. , Anderson P.S. , Freidinger R.M. 1989 Benzodiazepine gastrin and brain cholecystokinin receptor ligands: L-365, 260 Journal of Medicinal Chemistry 32: 13-16

Bouras C. , Schultz P. , Constantinidis J. , Tissot R. 1986 Differential effects of acute and chronic administration of haloperidol on substance P and enkephalins in diverse rat brain areas Neuropsychopharmacology 16: 169-174

Bozarth M.A. , Wise R.A. 1981 Heroin reward is dependent on a dopaminergic substrate Life Sciences 29: 1881-1886

Brambilla F. , Aguglia E. , Massironi R. , Maggiom M. , Grillo W. , Castiglioni R. , Catalano M. , Drago F. 1986 Neuropeptide therapies in chronic schizophrenia: TRH and vasopressin administration Neuropsychobiology 15: 114-121

Brodie M.S. , Dunwiddie T.V. 1987 Cholecystokinin potentiates dopamine inhibition of mesencephalic dopamine neurons in vitro Brain Research 425: 106-113

Broekkamp C.L. , Phillips A.G. , Cools A.R. 1979 Facilitation of self-stimulation behavior following intracerebral microinjection of opioids into the ventral tegmental area Pharmacology, Biochemistry and Behaviour 11: 289-295

Broekkamp C.L. , LePichon M. , Lloyd K.G. 1984 Akinesia after locally applied morphine near the nucleus raphe pontis of the rat Neuroscience Letters 50: 313-318

Brown M. , Vale W. 1975 Central nervous system effects of hypothalamic peptides Endocrinology 96: 1333-1336

Brownstein M.J. , Palkovits M. , Saavedra J.M. , Bassiri R.M. , Utiger R.D. 1974 Thyrotropin-releasing hormone in specific nuclei of rat brain Science 185: 267-269

Bruyn G. 1973 Neuropathological changes in Huntington's chorea In: Barbeau A., Chase T N, Paulson G W (eds). Huntington's chorea 1872-1972. New York: Raven Press , pp. 399-403

Buck S.H. , Burcher E. 1986 The tachykinins: a family of peptides with a brood of 'receptors' Trends in Pharmacological Science 7: 65-68

Buck S.H. , Helke C.J. , Burcher E. , Shults C.W. , O'Donohue T.L. 1986 Pharmacologic characterization and autoradiographic distribution of binding sites for iodinated tachykinins in the rat central nervous system Peptides 7: 1109-1120

Carino M.A. , Smith J.R. , Weick B.G. , Horita A. 1976 Effects of thyrotropin-releasing hormone (TRH) microinjected into various brain areas of conscious and pentobarbitalpretreated rabbits Life Sciences 19: 1687-1692

Chang R S L , Lotti V.J. 1986 Biochemical and pharmacological characterization of an extremely potent and selective non-peptide cholecystokinin antagonist Proceedings of the National Academy of Sciences USA 83: 4923-4926

Chang R S L , Lotti V.J. , Martin G.E. , Chen T.B. 1983 Increase in brain 125I-cholecystokinin (CCK) receptor binding following chronic haloperidol treatment, intracisternal 6-hydroxydopamine or ventral tegmental lesions Life Sciences 32: 871-878

Charpentier B. , Pelaprat D. , Durieux C. , Dor A. , Reibaud M. , Blanchard J-C. , Roques B.P. 1988 Cyclic cholecystokinin analogues with high selectivity for central receptors Proceedmgs of the National Academy of Sciences USA 85: 1968-1972

Chavkin C. , James I.F. , Goldstein A. 1982 Dynorphin is a specific endogenous ligand of the kappa opioid receptor Science 215: 413-415

Cheramy A. , Michelot R. , Leviel V. , Nieoullon A. , Glowinski J. , Kerdelhue B. 1978 Effect of the immunoneutralization of substance P m the cat substantia nigra on the release of dopamine from dendrites and terminals of dopaminergic neurons Brain Reseach 155: 404-408

Chesselet M-F. , Reisine T. 1983 Somatostatin regulates dopamme release in rat striatal slices and cat caudate nuclei Journal of Neuroscience 3: 232-236

Chiodo L.A. , Bunney B.S. 1987 Population response of midbrain dopaminergic neurons to neuroleptics: further studies on time course and nondopaminergic neuronal influences Journal of Neuroscience 7: 629-633

Conzelmann U. , Holland A. , Meyer D.K. 1984 Effects of selective dopamine D2-receptor agonists on the release of cholecystokinin-like immunoreactivity from rat neostriatum European Journal of Pharmacology 101: 119-125

Cooper P.E. , Fernstrom M.H. , Rorstad O.P. , Leeman S.E. , Martin J.B. 1981 The regional distribution of somatostatin, substance P and neurotensin in human brain Brain Research 218: 219-232

Costall B. , Hui S-C G , Metcalf G. , Naylor R.J. 1979 A study of the changes in motor behaviour caused by TRH on intracerebral injection European Journal of Pharmacology 53: 143-150

Crawley J.N. 1988 Neuronal cholecystokinin ISI Atlas of Science: Pharmacology; 84-90

Crawley J.N. , Hommer D.W. , Skirboll L.R. 1984 Behavioural and neurophysiological evidence for a facilitatory interaction between co-existing transmitters: cholecystokinin and dopamine Neurochemistry International 6: 755-760

Crowley W.R. , Shyr S-W. , Kacsoh B. , Grosvenor C.E. 1987 Evidence for stimulatory noradrenergic and inhibitory dopaminergic regulation of oxytocin release in the lactating rat Endocrinology 121: 14-20

Cuello A.C. , Kanazawa I. 1978 The distribution of substance P immunoreactive fibers m the rat central nervous system Journal of Comparative Neurology 178: 129-156

Cuello A.C. , Paxinos G. 1978 Evidence for a long Leuenkephalin striopallidal pathway in rat brain Nature 271: 178-180

Davies J. , Dray A. 1976 Substance P in the substantia nigra Brain Research 1976: 623-627

Davies P. , Katzman R. , Terry R.D. 1980 Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementia Nature 288: 279-280

Davies S.W. , Roberts P.J. 1987 No evidence for preservation of somatostatin-containing neurons after intrastriatal injections of quinolinic acid Nature 327: 326-329

Davis G.C. , Bunney W.E. , DeFraites E.G. , Kleinman J.E. , van Kammen D.P. , Post R.M. , Wyatt R.J. 1977 Intravenous naloxone administration in schizophrenia and affective illness Science 197: 74-76

Delay-Goyet P. , Zajac J-M. , Javoy-Agid F. , Agid Y. , Roques B.P. 1987 Regional distribution of mu, delta and kappa opioid receptors in human brains from controls and parkinsonian subjects Brain Research 414: 8-14

DeQuidt M.E. , Emson P.C. 1983 Neurotensin facilitates dopamine release in vitro from rat striatal slices Brain Research 274: 376-380

Dettmar P.W. , Cowan A. , Walter D.S. 1978 Naloxone antagonizes behavioural effects of d-amphetamine in mice and rats Neuropharmacology 17: 1041-1044

Deutch A.Y. , Bean A.J. , Roth R.H. 1988 Regulation of A8 dopamine neurons by somatostatin European Journal of Pharmacology 147: 317-320

Dumbrille-Ross A. , Seeman P. 1984 Dopamine receptor elevation by cholecystokinin Peptides 5: 1207-1212

Eison A.S. , Eison M.S. , Iversen S.D. 1982a The behavioural effects of a novel substance P analogue following infusion into the ventral tegmental area or substantia nigra of rat brain Brain Research 238: 137-152

Eison A. , Iversen S.D. , Sandberg B E B , Watson S.P. , Hanley M.R. , Iversen L.L. 1982 Substance P analog, DiMe-C7: evidence for stability in rat brain and prolonged central actions Science 215: 188-190

Elliott P.J. , Nemeroff C.B. , Kilts C.D. 1986 Evidence for a tonic facilitatory influence of substance P on dopamine release in the nucleus accumbens Brain Research 385: 379-382

Elliott P.J. , Alpert J.E. , Bannon M.J. , Iversen S.D. 1986 Selective activation of mesolimbic and mesocortical dopamine metabolism in rat brain by infusion of a stable substance P analogue into the central tegmental area Brain Research 363: 145-147

Emson P.C. , Arregui A. , Clement-Jones V. , Sandberg B.E. , Rossor M.N. 1980a Regional distribution of methionine enkephalin and substance P-like immunoreactivity in normal human brain and in Huntington's disease Brain Research 199: 147-160

Emson P.C. , Rehfeld J.F. , Rossor M.N. , Langevin H. 1980b Reductions in cholecystokinin-like immunoreactivity in the basal ganglia in Huntingtons' disease Brain Research 198: 497-500

Epelbaum J. , Ruberg M. , Moyse E. , Javoy-Agid F. , Dubois B. , Agid Y. 1983 Somatostatin and dementia in Parkinson's disease Brain Research 278: 376-379

Epelbaum J. , Javoy-Agid F. , Hirsch E. , Hauw J.J. , Kordon C. , Agid Y. , Krantic S. 1987 Brain somatostatin concentrations do not decrease in progressive supranuclear palsy Journal of Neurology, Neurosurgery and Psychiatry 50: 1526-1528

Ervin G.N. , Birkemo L.S. , Nemeroff C.B. , Prange A.J. 1981a Neurotensin blocks certain amphetamine-induced behaviours Nature 291: 73-76

Ervin G.N. , Schmitz S.A. , Nemeroff C.B. , Prange A.J. 1981b Thyrotropin-releasing hormone and amphetamine produce different patterns of behavioural excitation in rats European Journal of Pharmacology 72: 35-43

Farmery S.M. , Owen F. , Poulter M. , Crow T.J. 1985 Reduced high affinity cholecystokinin binding in hippocampus and frontal cortex of schizophrenic patients Life Sciences 36: 473-477

Ferrier I.N. , Roberts G.W. , Crow T.J. , Johnstone E.C. , Owens D G C , Lee Y.C. , O'Shaughnessy D. , Adrian T.E. , Polak J.M. , Bloom S.R. 1983 Reduced cholecystokinin-like and somatostatin-like immunoreactivity in limbic lobe is associated with negative symptoms in schizohrenia Life Sciences 33: 475-482

Finnerty E.P. , Chan S H H 1981 The participation of substantia nigra zona compacta and zona reticulata neurons in morphine suppression of caudate spontaneous neuronal activities in the rat Neuropharmacology 20: 241-246

Foster A.C. , Tridgett R. 1988 Comparison of the binding of radiolabelled neurokinin A and eledoisin in rat cortex synaptic membranes British Journal of Pharmacology 94: 602-608

Frey P. 1983 Cholecystokinin octapeptide levels in rat brain are changed after subchronic neuroleptic treatment European Journal of Pharmacology 95: 87-92

Fukamauchi F. , Yoshikawa T. , Kaneno S. , Shibuya H. , Takahashi R. 1987a Dopaminergic agents affected neuronal transmission of cholecystokinin in the rat brain Neuropeptides 10: 207-220

Fukamauchi F. , Yoshikawa T. , Kaneno S. , Shibuya H. , Takahashi R. 1987b The chronic administration of dopamine antagonists and methamphetamine changed the [3H]-cholecystokinin-8 binding sites in the rat frontal cortex Neuropeptides 10: 221-225

Fuxe K. , Andersson K. , Locatelli V. , Agnati L. , Hokfelt T. , Mutt V. , Skirboll L. 1980 Cholecystokinin peptides produce marked reduction of dopamine turnover in discrete areas in the rat brain following intraventricular injection European Journal of Pharmacology 67: 329-331

Fuxe K. , Agnati L. , Benfenati F. , Cimmino M. , Algeri S. , Hokfelt T. , Mutt V. 1981 Modulation by cholecystokinins of 3H-spiroperidol binding in rat striatum: evidence for increased affinity and reduction in the number of binding sites Acta Physiologica Scandinavica 113: 567-569

Gauchy C. , Agid Y. , Glowinski J. , Cheramy A. 1973 Acute effects of morphine on dopamine synthesis and release and tyrosine metabolism in the rat striatum European Journal of Pharmacology 22: 311-319

Gaudreau P. , Crawley J.N. , Quirion R. 1986 Effect of chronic haloperidol treatment on brain cholecystokinin receptors in rat Society of Neuroscience Abstracts 12: 832

Gaudreau P. , Quirion R. , St.Pierre S. , Chiueh C.C. , Pert A. 1987 Localization of cholecystokinin receptors in relation to the nigrostriatal and mesolimbic pathways Neuropeptides 9: 283-293

Gilbert P.E. , Martin W.R. 1976 The effects of morphine-and nalorphine-like drugs in the nondependent, morphine-dependent and cyclazocine-dependent chronic spinal dog Journal of Pharmacology and Experimental Therapeutics 198: 66-82

Govoni S. , Hong J.S. , Yang H-Y T , Costa E. 1980 Increase of neurotensin content elicited by neuroleptics in nucleus accumbens Journal Pharmacology and Experimental Therapeutics 215: 413-417

Gysling K. , Wang R.Y. 1983 Morphine-induced activation of A10 dopamine neurons in the rat Brain Research 277: 119-127

Haber S. , Hatsukami T. , Berger P. , Barchas J. , Akil H. 1978 Naloxone blocks amphetamine-induced rearing - potential interaction between catecholamines and endorphins Progress in Neuropsychopharmacology 2: 425-430

Haber S.N. , Kowall N.W. , Vonsattel J.P. , Bird E.D. , Richardson E.P. 1986 Gilles de la Tourette's syndrome. A postmortem neuropathological and immunohistochemical study Journal of Neurological Science 75: 225-241

Hand T.H. , Franklin K B J 1985 6-OHDA lesions of the ventral tegmental area block morphine-induced but not amphetamine-induced facilitation of self-stimulation Brain Research 328: 233-241

Hanson G.R. , Letter A.E. , Merchant K. , Gibb J.W. 1986 Comparison of responses by striatonigral substance P and neurokinin A systems to methamphetamine treatment Peptides 7: 983-987

Hanson G.R. , Merchant K.M. , Letter A.A. , Bush L. , Gibb J.W. 1987 Methampthetamine-induced changes in the striatal-nigral dynorphin system: role of D-1 and D-2 receptors European Journal of Pharmacology 144: 245-246

Hanson H. , Cimini C. 1974 Effects of administration of haloperidol on morphine self-administration in the rat Clinical Toxicology 7: 273-280

Hays S.E. , Meyer D.K. , Paul S.M. 1981 Localization of cholecystokinin receptors to neuronal elements in the rat caudate nucleus Brain Research 219: 208-213

Heal D.J. , Sabbagh A. , Youdim M B H , Green A.R. 1981 Behavioural effects of central and peripheral injection of various analogue and metabolites of thyrotopin releasing hormone (TRH) Neuropharmacology 20: 947-957

Herkenham M. 1987 Mismatches between neurotransmitter and receptor localizations in brain: observations and implications Neurosciences 23: 1-38

Herrera-Marschitz M. , Christensson-Nylander I. , Sharp T. , Staines W. , Reid M. , Hokfelt T. , Terenius L. , Ungerstedt U. 1986 Striato-nigral dynorphin and substance P pathways in the rat. II. Functional analysis Experimental Brain Research 64: 193-207

Hill D.R. , Shaw T.M. , Woodruff G.N. 1987 Species differences in the localization of 'peripheral' type cholecystokinin receptors in rodent brain Neuroscience Letters 79: 286-289

Hill D.R. , Shaw T.M. , Woodruff G.N. 1988 Binding sites for 125I-Cholecystokinin in primate spinal cord are of the CCK-A subclass Neuroscience Letters 89: 133-139

Hill D.R. , Campbell N.J. , Shaw T.M. , Woodruff G.N. 1987 Autoradiographic localization and biochemical characterization of peripheral type CCK receptors in rat CNS using highly selective nonpeptide CCK antagonists Journal of Neuroscience 7: 2967-2976

Hokfelt T. , Everitt B.J. , Theodorsson-Norheim E. , Goldstem M. 1984 Occurrence of neurotensin like immunoreactivity in subpopulations of hypothalamic, mesencephalic, and medullary catecholamine neurons Journal of Comparative Neurology 222: 543-559

Hokfelt T. , Fuxe K. , Johansson O. , Jeffcoate S. , White N. 1975 Distribution of thyrotropin-releasing hormone (TRH) in the central nervous system as revealed with immunohistochemistry European Journal of Pharmacology 34: 389-392

Hokfelt T. , Herrera-Marschitz M. , Seroogy K. , Ju G. , Stames W.A. , Holets V. , Schalling M. , Ungerstedt U. , Post C. , Rehfeld J.F. , Frey P. , Fischer J. , Dockray G. , Hamaoka T. , Walsh J.H. , Goldstein M. 1988 Immunohistochemical studies on cholecystokinin (CCK)-immunoreactive neurons in the rat using sequence specific antisera and with special reference to the caudate nucleus Journal of Chemical Neuroanatomy 1: 11-52

Hokfelt T. , Meister B. , Everitt B. , Staines W. , Melander T. , Schalling M. , Mutt V. , Hulting A-L. , Werner S. , Bartfai T. , Nordstrom O. , Fahrenkrug J. , Goldstein M. 1987a Chemical neuroanatomy of the hypothalamo-pituitary axis: focus on multimessenger systems In: McCann S M, Weiner R I eds Integrative neuroendocrinology: molecular, cellular and clinical aspects. Basel: Karger, pp. 1-34

Hokfelt T. , Millhorn D. , Seroogy K. , Tsuruo Y. , Ceccatelli S. , Lmdh B. , Meister B. , Melander T. , Schalling M. , Bartfai T. , Teremus L. 1987b Coexistence of peptides with classical neurotransmitters Experientia 43: 768-780

Hokfelt T. , Skirboll L. , Rehfeld J.F. , Goldstein M. , Markey K. , Dann O. 1980 A subpopulation of mesencephalic dopamine neurons projecting to limbic areas contains a cholecystokinin-like peptide: evidence from immunohistochemistry combined with retrograde tracing Neuroscience 5: 2093-2124

Hommer D.W. , Pert A. 1983 The actions of opiates in the rat substantia nigra: an electrophysiological analysis Peptides 4:603-608

Hommer D.W. , Skirboll L.R. 1983 Cholecystokinin-like peptides potentiate apomorphine-induced inhibition of dopamine neurons European Journal of Pharmacology 91: 151-152

Hong J.S. , Yang H-Y T , Fratta W. , Costa E. 1978 Rat striatal methionine-enkephalin content after chronic treatment with cataleptogemc and noncataleptogenic antischizophremc drugs Journal of Pharmacology and Experimental Therapeutics 205: 141-147

Hong J.S. , Yang H-Y T , Gillin J.C. , DiGiulio A.M. , Costa E. 1979 Chromc treatment with haloperidol accelerates the biosynthesis of enkephalins in rat striatum Brain Research 160: 192-195

Horst S.D. , Spirt N. 1974 A possible mechanism for the antidepressant activity of thyrotropin releasing hormone Life Sciences 15: 1073-1082

Innis R.B. , Andrade R. , Aghajanian G.K. 1985 Substance K excites dopaminergic and non-dopaminergic neurons in rat substantia nigra Brain Research 335: 381-383

Iversen S.D. 1981 Neuropeptides: do they integrate body and brain? Nature 291: 454

Iwamoto E.T. , Way E.L. 1977 Circling behavior and stereotypy induced by intranigral opiate microinjections Journal of Pharmacology and Experimental Therapeutics 203: 347-359

Iwatsubo K. , Clouet D.H. 1977 Effects of morphine and haloperidol on the electrical activity of rat nigrostriatal neurons Journal of Pharmacology and Experimental Therapeutics 202: 429-436

Jacquet Y.F. , Marks N. 1976 The C-fragment of β-lipotropin: an endogenous neuroleptic or antipsychotogen? Science 194: 632-635

James T.A. , Starr M.S. 1979 Effects of substance P injected into the substantia nigra British Journal of Pharmacology 65: 423-429

Javoy-Agid F. , Grouselle D. , Tixier-Vidal A. , Agid Y. 1983 Thyrotropin releasing hormone content is unchanged in brains of patients with Parkinson disease Neuropeptides 3: 405-410

Jenner P. , Taquet H. , Mauborgne A. , Benoliel J.T. , Cesselin F. , Rose S. , Javoy-Agid F. , Agid Y. , Marsden C.D. 1986 Lack of change in basal ganglia neuropeptide content following subacute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of the common marmoset Journal of Neurochemistry 47: 1548-1551

Jerussi T.P. , Capacchione J.F. , Benvenga M.J. 1987 Reversal of opioid-induced muscular rigidity in rats: evidence for alpha-2 adrenergic involvement Pharmacology, Biochemistry and Behaviour 28: 283-289

Jones E.G. , Hendry S H C 1986 Co-localization of GABA and neuropeptides in neocortical neurons Trends in Neuroscience 9: 71-76

Joyce E.M. , Iversen S.D. 1979 The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous motor activity in the rat Neuroscience Letters 14: 207-212

Joyce E.M. , Koob G.F. , Strecker R. , Iversen S.D. , Bloom F.E. 1981 The behavioural effects of enkephalin analogues injected into the ventral tegmental area and globus pallidus Brain Research 221: 359-370

Kalivas P.W. , Abhold R. 1987 Enkephalin release into the ventral tegmental area in response to stress: modulation of mesocorticolimbic dopamine Brain Research 414: 339-348

Kalivas P.W. , Miller J.S. 1984 Neurotensin neurons in the ventral tegmental area project to the medial nucleus accumbens Brain Research 300: 157-160

Kalivas P.W. , Nemeroff C.B. , Prange A.J. 1984 Neurotensin microinjection into the nucleus accumbens antagonizes dopamine-induced increase in locomotion and rearing Neuropharmacology 11: 919-930

Kalivas P.W. , Stanley D. , Prange A.J. 1987 Interaction between thryrotropin-releasing hormone and the mesolimbic dopamine system Neuropharmacology 26: 33-38

Kalivas P.W. , Burgess S.K. , Nemeroff C.B. , Prange A.J. 1983 Behavioral and neurochemical effects of neurotensin microinjection into the ventral tegmental area of the rat Neuropharmacology 8: 495-505

Kalivas P.W. , Deutch A.Y. , Maggio J.E. , Mantyh P.W. , Roth R.H. 1985 Substance K and substance P in the ventral tegmental area Neuroscience Letters 57: 241-246

Kanazawa I. , Emson P.C. , Cuello A.C. 1977 Evidence for the existence of substance P-containing fibres in striato-nigral and pallido-nigral pathways in rat brain Brain Research 119: 447-453

Kanazawa I. , Bird E.D. , O'Connell R. , Powell D. 1977 Evidence for a decrease in substance P content of substantia nigra in Huntington's chorea Brain Research 120: 387-392

Kanazawa I. , Ogawa T. , Kimura S. , Munekata E. 1984 Regional distribution of substance P, neurokinin A and neurokinin B in rat central nervous system Neuroscience Research 2: 111-120

Kangawa K. , Minamino N. , Fukuda A. , Matsuo H. 1983 Neuromedin K: a novel mammalian tachykinin identified in porcine spinal cord Biochemical and Biophysical Research Communications 114: 533-540

Katsuura G. , Itoh S. , Rehfeld J.F. 1984 Effects of cholecystokinin on apomorphine-induced changes of motility in rats Neuropharmacology 23: 731-734

Kelley A.E. , Iversen S.D. 1978 Behavioural response to bilateral injections of substance P into the substantia nigra of the rat Brain Research 158: 474-478

Kelley A.E. , Iversen S.D. 1979 Substance P infusion into substantia mgra of the rat: behavioural analysis and involvement of striatal dopamine European Journal of Pharmacology 60: 171-179

Kelley A.E. , Stinus L. , Iversen S.D. 1979 Behavioural activation induced in the rat by substance P infusion into ventral tegmental area: implication of dopaminergic A10 neurons Neuroscience Letters 11: 335-339

Kelley A.E. , Stinus L. , Iversen S.D. 1980 Interactions between D-Ala-Met-enkephalin, A10 dopaminergic neurones, and spontaneous behaviour in the rat Behavioural Brain Research 1: 3-24

Kelly P.H. , Seviour P.W. , Iversen S.D. 1975 Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum Brain Research 94: 507-522

Kerwm R.W. , Pycock C.J. 1979 Thyrotropin releasing hormone stimulates release of [ 3H]-dopamine from slices of rat nucleus accumbens in vitro British Journal of Pharmacology 67: 323-325

Kilts C.D. , Anderson C.M. , Bissette G. , Ely T.D. , Nemeroff C.B. 1988 Differential effects of antipsychotic drugs on the neurotensin concentration of discrete rat brain nuclei Biochemical Pharmacology 37: 1547-1554

Kiraly I. , van Ree J.M. 1987 Behavioural evidence for the involvement of endogenous opioids in the interaction between cholecystokinin and brain dopamine systems Neuroscience Letters 74: 343-347

Klawans H.L. , Rubovits R. 1972 Central cholinergic-anticholinergic antagonism in Huntington's chorea Neurology 22: 107-116

Kleinman J.E. , Iadarola M. , Govoni S. , Hong J. , Gillin J.C. , Wyatt R.J. 1983 Postmortem measurements of neuropeptides in human brain. Psychopharmacology Bulletin 19: 375-377

Kobayashi R.M. , Brown M. , Vale W. 1977 Regional distribution of neurotensin and somatostatin in rat brain Brain Research 126: 584-588

Kondo Y. , Iwatsubo K. 1980 Diminished responses of nigral dopaminergic neurons to haloperidol and morphine following lesions in the striatum Brain Research 181: 237-240

Kubek M.J. , Lorincz M.A. , Wilber J.F. 1977 The identification of thyrotropin releasing hormone (TRH) in hypothalamic and extrahypothalamic loci of the human nervous system Brain Research 126: 196-200

Kubota Y. , Inagaki S. , Kito S. 1986 Innervation of substance P neurons by catecholaminergic terminals in the neostriatum Brain Research 375: 163-167

Kuhar M.J. , Pert C.B. , Snyder S.H. 1973 Regional distribution of opiate receptor binding in monkey and human brain Nature 245: 447-450

Lane R.F. , Blaha C.D. , Phillips A.G. 1986 In vivo electrochemical analysis of cholecystokinin-induced inhibition of dopamine release in the nucleus accumbens Brain Research 397: 200-204

Laufer R. , Wormser U. , Friedman Z.Y. , Gilon C. , Chorev M. , Selinger Z. 1985 Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin. Proceedings of the National Academy of Sciences USA 82: 7444-7448

Lee C-M. , Iversen L.L. 1981 Release of somatostatin from extra-hypothalamic rat brain slices: inhibition by dopamine and morphine Brain Research 219: 355-361

Lee C-M. , Campbell N.J. , Williams B.J. , Iversen L.L. 1986 Multiple tachykinin binding sites in peripheral tissues and in brain European Journal of Pharmacology 130: 209-217

Lee J-M. , McLean S. , Maggio J.E. , Zamir N. , Roth R.H. , Eskay R.L. , Bannon M.J. 1986 The localization and characterization of substance P and substance K in striatonigral neurons Brain Research 371: 152-154

Letter A.A. , Matsuda L.A. , Merchant K.M. , Gibb J.W. , Hanson G.R. 1987 Characterization of dopaminergic influence on striatal-nigral neurotensin systems Brain Research 422: 200-203

Levy A.B. , Stern S.L. 1987 DST and TRH stimulation test in mood disorder subtypes American Journal of Psychiatry 144: 472-475

Li S. , Sivam S.P. , Hong J.S. 1986 Regulation of the concentration of dynorphin A1-8 in the striatomgral pathway by the dopaminergic system Brain Research 398: 390-392

Lindefors N. , Brodin E. , Ungerstedt U. 1986 Neuroleptic treatment induces region-specific changes in levels of neurokinin A and substance P in rat brain Neuropeptides 7: 265-280

Lmdvall O. , Bjorklund A. , Skagerberg G. 1983 Dopamine-containing neurons in the spinal cord: anatomy and some functional aspects Annals of Neurology 14: 255-260

Llorens-Cortes C. , Javoy-Agid F. , Agid Y. , Taquet H. , Schwartz J.C. 1984 Enkephalinergic markers in substantia nigra and caudate nucleus from Parkinsonian subjects Journal of Neurochemistry 43: 874-877

Lord J A H , Waterfield A.A. , Hughes J. , Kosterlitz H.W. 1977 Endogenous opioid peptides: multiple agomsts and receptors Nature 267: 495-499

Manaker S. , Winokur A. , Rostene W.H. , Rainbow T.C. 1985 Autoradiographic localization of thyrotropin-releasing hormone receptors in the rat central nervous system Journal of Neuroscience 5: 167-174

Mantyh P.W. , Hunt S.P. 1985 Thyrotropin-releasing hormone (TRH) receptors. Localization by light microscopic autoradiography in rat brain using [3H][3-Me-His 2]TRH as the radioligand Journal of Neuroscience 5: 551-561

Mantyh P.W. , Hunt S.P. , Maggio J.E. 1984 Substance P receptors: localization by light microscopic autoradiography in rat brain using [3H]SP as the radioligand Brain Research 307: 147-165

Mantyh P.W. , Maggio J.E. , Hunt S.P. 1984 The autoradiographic distribution of kassinin and substance K binding sites is different from the distribution of substance P binding sites in rat brain European Journal of Pharmacology 102: 361-364

Markstein R. , Hokfelt T. 1984 Effect of cholecystokinin-octapeptide on dopamine release from slices of cat caudate nucleus Journal of Neuroscience 4: 570-575

Martin J.B. , Reichlin S. 1987 Neuropharmacology of anterior pituitary regulation. In: Clinical neuroendocrinology Philadelphia : F A Davis, pp. 45-63

Martin J.R. , Beinfeld M.C. , Wang R.Y. 1986 Modulation of cholecystokinin release from posterior nucleus accumbens by D-2 dopamine receptor Brain Research 397: 253-258

Martin W.R. , Eades C.G. , Thompson J.A. , Huppler R.E. , Gilbert P.E. 1976 The effects of morphine- and nalorphinehke drugs in the nondependent and morphine-dependent chronic spinal dog Journal of Pharmacology and Experimental Therapeutics 197: 517-532

Martin-Iverson M.T. , Radke J.M. , Vincent S.R. 1986 The effects of cysteamine on dopamine-mediated behaviors: evidence for dopamine-somatostatin interactions in the striatum Pharmacology, Biochemistry and Behaviour 24: 1707-1714

Mashal R.D. , Owen F. , Deakin J F W , Poulter M. 1983 The effects of cholecystokinin on dopaminergic mechanisms in rat striatum Brain Research 277: 375-376

Matthews R.T. , German D.C. 1984 Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine Neuropharmacology 11: 617—625

Mauborgne A. , Javoy-Agid F. , Legrand J.C. , Agid Y. , Cesselin F. 1983 Decrease of substance P-like immunoreactivity in the substantia nigra and pallidum of parkinsonian brains Brain Research 268: 167-170

McKnight A.T. , Maguire J.J. , Varney M.A. , Williams B.J. , Iversen L.L. 1988 Characterization of tachykinin receptors using selectivity of agonists and antagonists: evidence for an NK-4 type Regulatory Peptides 22: 126

Meister B. , Hokfelt T. , Brown J. , Joh T. , Goldstein M. 1987 Dopaminergic cells in the caudal A13 cell group express somatostatin-like immunoreactivity Experimental Brain Research 67: 441-444

Meyer D.K. , Krauss J. 1983 Dopamine modulates cholecystokinin release in neostriatum Nature 301: 338-340

Michelot R. , Leviel V. , Giorguieff-Chesselet M. , Cheramy A. , Glowinski J. 1979 Effects of the unilateral nigral modulation of substance P transmission on the activity of the two nigrostriatal dopaminergic pathways Life Sciences 24: 715-724

Minamino N. , Kangawa K. , Fukuda A. , Matsuo H. 1984 Neuromedin L: a novel mammalian tachykinin identified in porcine spinal cord Neuropeptides 4: 157-166

Miyamoto M. , Nagawa Y. 1977 Mesolimbic involvement in the locomotor stimulant action of thyrotropin-releasing hormone (TRH) in rats European Journal of Pharmacology 44: 143-152

Miyamoto M. , Narumi S. , Nagai Y. , Shima T. , Nagawa Y. 1979 Thyrotropin-releasing hormone: hyperactivity and mesolimbic dopamine system in rats Japanese Journal of Pharmacology 29: 335-347

Moore K.E. 1987 Interactions between prolactin and dopaminergic neurons Biology of Reproduction 36: 47-58

Moran T.H. , Robinson P.H. , Goldrich M.S. , McHugh P.R. 1986 Two brain cholecystokinin receptors: implications for behavioural actions Brain Research 362: 175-179

Morelli M. , DiChiara G. 1985 Non-dopaminergic mechanisms in the turning behavior evoked by intranigral opiates Brain Research 341: 350-359

Morency M.A. , Ross G.M. , Hesketh D. , Mishra R.K. 1987 Effects of unilateral intracerebroventricular microinjections of cholecystokinin (CCK) on circling behaviour in rats Peptides 8: 989-995

Moroji T. , Hagino Y. 1986 A behavioural pharmacological study on CCK-8 related peptides in mice Neuropeptides 8: 273-286

Moser A. , Reavill C. , Jenner P. , Marsden C.D. , Cramer H. 1986 Effects of somatostatin on dopamine sensitive adenylate cyclase activity in the caudate-putamen of the rat Experimental Brain Research 62: 567-571

Myers R.D. , Lee T.F. 1983 In vivo release of dopamine during perfusion of neurotensin in substantia nigra of the unrestrained rat Peptides 4: 955-961

Nagashima A. , Takano Y. , Masui H. , Kamiya H. 1987 Evidence that neurokinin A (substance K) neurons project from the striatum to the substantia mgra in rats Neuroscience Letters 77: 103-108

Nakahara T. , Matsumoto T. , Hirano M. , Uchimura H. , Yokoo H. , Nakamura K. , Ishibashi K. , Hirano H. 1985 Effect of DN-1417, a thyrotropin releasing hormone analog, on dopaminergic neurons in rat brain Peptides 6: 1093-1099

Nemeroff C.B. , Bissette G. , Manberg P.J. , Osbahr A.J. , Breese G.R. , Prange A.J. 1980 Neurotensin-induced hypothermia: evidence for an interaction with dopaminergic systems and the hypothalamic-pituitary-thyroid axis Brain Research 195: 69-84

Nemeroff C.B. , Bissette G. , Prange A.G. , Loosen P.T. , Barlow T.S. , Lipton M.A. 1977 Neurotensin: central nervous system effects of a hypothalamic peptide Brain Research 128: 485-496

Nemeroff C.B. , Luttinger D. , Hernandez D.E. , Mailman R.B. , Mason G.A. , Davis S.D. , Breese G.R. , Prange A.J. 1983a Interactions of neurotensin with brain dopamine systems: biochemical and behavioral studies Journal of Pharmacology and Experimental Therapeutics 225: 337-345

Nemeroff C.B. , Youngblood W.W. , Manberg P.J. , Prange A.J. , Kizer J.S. 1983b Regional brain concentrations of neuropeptides in Huntington's chorea and schizophrenia Science 221: 972-975

Nielsen J.A. , Moore K.E. 1984 Thyrotropin-releasing hormone and its analog MK-777 increase the cerebroventricular perfusate content of dihydroxyphenylacetic acid Journal of Neurochemistry 43: 593-596

Nishikawa T. , Tanaka M. , Tsuda A. , Kuwahara H. , Koga I. , Uchida Y. 1986 Effect of ceruletide on tardive dyskinesia: a pilot study of quantitative computer analyses on electromyogram and microvibration Psychopharmacology 90: 5-8

Normand E. , Popovici T. , Fellmann D. , Bloch B. 1987 Anatomical study of enkephalin gene expression in the rat forebrain following haloperidol treatment Neuroscience Letters 83: 232-236

Nutt J.G. , Rosin A.J. , Eisler T. , Calne D.B. , Chase T.N. 1978 Effect of an opiate antagonist on movement disorders Archives of Neurology 35: 810-811

Nylander I. , Terenius L. 1986 Chronic haloperidol and clozapine differentially affect dynorphin peptides and substance P in basal ganglia of the rat Brain Research 380: 34-41

Nylander I. , Terenius L.H. 1987 Dopamine receptors mediate alterations in striato-nigral dynorphin and substance P pathways Neuropharmacology 26: 1295-1302

Ostrowski N.L. , Hatfield C.B. , Caggiula A.R. 1982 The effects of low doses of morphine on the activity of dopamine-containing cells and on behavior Life Sciences 31: 2347-2350

Owen F. , Bourne R.C. , Poulter M. , Crow T.J. , Paterson S.J. , Kosterlitz H.W. 1985 Tritiated etorphine and naloxone binding to opioid receptors in caudate nucleus in schizophrenia British Journal of Psychiatry 146: 507-509

Palacios J.M. , Kuhar M.J. 1981 Neurotensin receptors are located on dopamine-containing neurones in rat midbrain Nature 294: 587-589

Palkovits M. , Brownstein M.J. , Eiden L.E. , Beinfeld M.C. , Russell J. , Arimura A. , Szabo S. 1982 Selective depletion of somatostatin in rat brain by cysteamine Brain Research 240: 178-180

Phillips A.G. , LePiane F.G. 1980 Reinforcing effects of morphine microinjection into the ventral tegmental area Pharmacology, Biochemistry and Behaviour 12: 965-968

Phillips A.G. , LePiane F.G. 1982 Reward produced by microinjection of (D-Ala2)Met5-enkephalinamide into the ventral tegmental area Behavioural Brain Research 5: 225-229

Pinnock R.D. 1985 Neurotensin depolarizes substantia nigra dopamine neurons Brain Research 338: 151-154

Pinnock R.D. , Woodruff G.N. , Turnbull M.J. 1983 Actions of substance P, MIF, TRH and related peptides in the substantia nigra, caudate nucleus and nucleus accumbens Neuropharmacology 22: 687-696

Plotnikoff N.P. , Kastin A.J. , Schally A.V. 1974 Growth hormone release inhibiting hormone: neuropharmacological studies Pharmacology, Biochemistry and Behaviour 2: 693-696

Plotnikoff N.P. , Prange A.J. , Breese G.R. , Anderson M.S. , Wilson I.C. 1972 Thyrotropin-releasing hormone: enhancement of Dopa activity by a hypothalamic hormone Science 178: 417-418

Pollard H. , Llorens-Cortes C. , Schwartz J.C. 1977 Enkephalin receptors on dopaminergic neurones in rat striatum Nature 268: 745-747

Porter J.C. , Reymond M.J. , Arita J. , Sissom J.F. 1983 Secretion of hypothalamic dopamine into the hypophysial portal vasculature: an overview Methods in Enzymology 103: 607-618

Prange A.J. , Wilson I.C. , Lara P.P. , Alltop L.B. , Breese G.R. 1972 Effects of thyrotropin-releasing hormone in depression Lancet 6: 999-1002

Quirion R. 1985 Multiple tachykinin receptors Trends in Neuroscience 8: 183-185

Quirion R. 1988 Atrial natriuretic factors and the brain: an update Trends in Neuroscience 11: 58-62

Quirion R. , Dam T-V. 1985 Multiple tachykinin receptors in guinea pig brain, high densities of substance K (neurokinin A) binding sites in the substantia nigra Neuropeptides 6: 191-204

Quirion R. , Chiueh C.C. , Everist H.D. , Pert A. 1985a Comparative localization of neurotensin receptors on nigrostriatal and mesolimbic dopaminergic terminals Brain Research 327: 385-389

Quirion R. , Gaudreau P. , Martel J-C. , St-Pierre S. , Zamir N. 1985b Possible interactions between dynorphin and dopaminergic systems in rat basal ganglia and substantia nigra Brain Research 331: 358-362

Quirion R. , Welner S. , Gauthier S. , Bedard P. 1987 Neurotensin receptor binding sites in monkey and human brain: autoradiographic distribution and effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment Synapse 1: 559-566

Quock R.M. 1977 The potentiating effect of naloxone upon apomorphine-induced hyperthermia Life Sciences 20: 2005-2012

Quock R.M. 1982 Naloxone potentiation of apomorphinemduced stereotypic climbing in mice and interaction with mu-, sigma- and kappa-opiate drugs Life Science 31: 2907-2911

Quock R.M. , Lucas T.S. 1981 Enhancement of apomorphine-induced climbing in mice by reversible and irreversible narcotic antagonist drugs Life Sciences 28: 1421-1424

Radke J.M. , Cumming P. , Vincent S.R. 1987 Effects of MPTP poisoning on central somatostatin and substance P levels in the mouse European Journal of Pharmacology 134: 105-108

Radke J.M. , MacLennan A.J. , Vincent S.R. , Fibiger H.C. 1988 Comparison between short- and long-term haloperidol administration on somatostatin and substance P concentrations in the rat brain Brain Research 445: 55-60

Regoli D. , Drapeau G. , Dion S. , D'Orleans-Juste P. 1987 Pharmacological receptors for substance P and neurokinins Life Sciences 40: 109-117

Reiner A. 1986 The co-occurrence of substance P-like immunoreactivity and dynorphin-like immunoreactivity in striatopallidal and striatonigral projection neurons in birds and reptiles Brain Research 371: 155-161

Reisine T.D. , Rossor M. , Spokes E. , Iversen L.L. , Yamamura H.I. 1979 Alterations in brain opiate receptors in Parkinson's disease Brain Research 173: 378-382

Rezek M. , Havlicek V. , Hughes K.R. , Friesen H. 1977a Behavioural and motor excitation and inhibition induced by the administration of small and large doses of somatostatin into the amygdala Neuropharmacology 16: 157-162

Rezek M. , Havlicek V. , Leybm L. , Pmsky C. , Kroeger E.A. , Hughes K.R. , Friesen H. 1977b Neostriatal administration of somatostatin: differential effect of small and large doses on behavior and motor control Canadian Journal of Physiology and Pharmacology 55: 234-242

Ritter J.K. , Schmidt C.J. , Gibb J.W. , Hanson G.R. 1984 Increases of substance P-like immunoreactivity within striatal-nigral structures after subacute methamphetamine treatment Journal of Pharmacol and Experimental Therapeutics 229: 487-492

Ritter J.K. , Schmidt C.J. , Gibb J.W. , Hanson G.R. 1985 Dopamine-mediated increases in mgral substance P-like immunoreactivity Biochemistry and Pharmacology 34: 3161-3166

Roberts G.W. , Ferrier I.N. , Lee Y.C. , Crow T.J. , Johnstone E.C. , Owens D C G , Hamilton A. , Polak J.M. , Bloom S.R. 1983 Peptides, the limbic lobe and schizophrenia Brain Research 288: 199-211

Rossor M.N. , Emson P.C. , Mountjoy C.Q. , Roth M. , Iversen L.L. 1980 Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type Neuroscience Letters 20: 373-377

Saffroy M. , Beaujouan J-C. , Torrens Y. , Besseyre J. , Bergstrom L. , Glowinski J. 1988 Localization of tachykinin binding sites (NK1, NK2, NK3 ligands) in the rat brain Peptides 9: 227-241

Saito A. , Sankaran H. , Goldfine I.D. , Williams J.A. 1980 Cholecystokinin receptors in the brain: characterization and distribution Science 208: 1155-1156

Sarrieau A. , Javoy-Agid F. , Kitabgi P. , Dussaillant M. , Vial M. , Vincent J.P. , Agid Y. , Rostene W.H. 1985 Characterization and autoradiographic distribution of neurotensin binding sites in the human brain Brain Research 348: 375-380

Schenkel-Hulliger L. , Koella W.P. , Hartmann A. , Maitre L. 1974 Tremorogenic effect of thyrotropin releasing hormone in rats Experientia 30: 1168-1170

Schwarcz R. , Fuxe K. , Hokfelt T. , Terenius L. , Goldstein M. 1980 Effects of chronic striatal kainate lesions on some dopaminergic parameters and enkephalin immunoreactive neurons in the basal ganglia Journal of Neurochemistry 34: 772-778

Seizinger B.R. Liebisch D.C. , Kish S.J. , Arendt R.M. , Hornykiewicz O. , Herz A. 1986 Opioid peptides in Huntington's disease: alterations in prodynorphin and proenkephalin system Brain Research 378: 405-408

Seroogy K.B. , Mehta A. , Fallon J.H. 1987 Neurotensin and cholecystokinin coexistence within neurons of the ventral mesencephalon: projections to forebrain Experimental Brain Research 68: 277-289

Sharp T. , Bennett G.W. , Marsden C.A. 1982 Thyrotropin-releasing hormone analogues increase dopamine release from slices of rat brain Journal of Neurochemistry 39: 1763-1766

Sharp T. , Brazell M.P. , Bennett G.W. , Marsden C.A. 1984 The TRH analogue CG3509 increases in vivo catechol/ ascorbate oxidation in the n. accumbens but not in the striatum of the rat Neuropharmacology 23: 617-623

Shults C. , Steardo L. , Barone P. , Mohr E. , Juncos J. , Serrati C. , Fedio P. , Tamminga C.A. , Chase T.N. 1986 Huntington's disease: effect of cysteamine, a somatostatin-depleting agent Neurology 36: 1099-1102

Skirboll L.R. , Grace A.A. , Hommer D.W. , Rehfeld J. , Goldstein M. , Hokfelt T. , Bunney B.S. 1981 Peptide-monoamine coexistence: studies of the actions of cholecystokinin-like peptide on the electrical activity of midbrain dopamine neurons Neuroscience 6: 2111-2124

Slater P. , Cross A.J. 1986 Autoradiographic distribution of dynorphin19 binding sites in primate brain Neuropeptides 8: 71-76

Sonsalla P.K. , Gibb J.W. , Hanson G.R. 1986 Nigrostriatal dopamine actions on the D2 receptors mediate methamphetamine effects on the striatonigral substance P system Neuropharmacology 25: 1221-1230

Spindel E.R. , Wurtman R.F. , Bird E.D. 1980 Increased TRH content of the basal ganglia in Huntington's disease New England Journal of Medicine 303: 1235-1236

Spyraki C. , Fibiger H.C. , Phillips A.G. 1983 Attenuation of heroin reward in rats by disruption of the mesolimbic dopamine system Psychopharmacology 79: 278-283

Steele J.C. , Richardson J.C. , Olszewski J. 1964 Progressive supranuclear palsy Archives of Neurology 10: 333-359

Stinus L. , Kelley A.E. , Iversen S.D. 1978 Increased spontaneous activity following substance P infusion into A10 dopaminergic area Nature 276: 616-618

Stoessl A.J. , Dourish C.T. , Iversen S.D. 1989 Chronic neuroleptic-induced mouth movements in the rat: suppression by CCK and selective dopamine D1 and D2 receptor antagonists Psychopharmacology 98: 372-379.

Studler J.M. , Javoy-Agid F. , Cesselin F. , Legrand J.C. , Agid Y. 1982 CCK-8-immunoreactivity distribution in human

brain: selective decreases in the substantia nigra from parkinsonian patients Brain Research 243: 176-179

Studler J.M. , Reibaud M. , Herve D. , Blanc G. , Glowinski J. , Tassin J.P. 1986 Opposite effects of sulfated cholecystokinin on DA-sensitive adenylate cyclase in two areas of the rat nucleus accumbens European Journal of Pharmacology 126: 125-128

Takano Y. , Takeda Y. , Yamada K. , Kamiya H. 1985 Substance K, a novel tachykinin injected bilaterally into the ventral tegmental area of rats increases behavioural response Life Sciences 37: 2507-2514

Taquet H. , Javoy-Agid F. , Hamon M. , Legrand J.C. , Agid Y. , Cesselin F. 1983 Parkinson's disease affects differently Met5- and Leu5-enkephalin in the human brain Brain Research 280: 379-382

Taquet H. , Javoy-Agid F. , Giraud P. , Legrand J.C. , Agid Y. , Cesselin F. 1985 Dynorphin levels in parkinsonian patients: Leu5-enkephalin production from either proenkephalin A or prodynorphin in human brain Brain Research 341: 390-392

Taquet H. , Javoy-Agid F. , Mauborgne A. , Benoliel J.J. , Agid Y. , Legrand J.C. , Hamon M. , Cesselin F. 1987 Brain neuropeptides in progressive supranuclear palsy Brain Research 411: 178-182

Tatsuoka Y. , Riskind P.N. , Beal M.F. , Martin J.B. 1987 The effect of amphetamine on the in vivo release of dopamine, somatostatin and neuropeptide Y from rat caudate nucleus Brain Research 411: 200-203

Thal L.J. , Laing K. , Horowitz S.G. , Makman M.H. 1986 Dopamine stimulates rat cortical somatostatin release Brain Research 372: 205-209

Tran V.T. , Beal M.F. , Martin J.B. 1985 Two types of somatostatin receptors differentiated by cyclic somatostatin analogs Science 228: 492-495

Tran V.T. , Uhl G.R. , Perry D.C. , Manning D.C. , Vale W.W. , Perrin M.H. , Rivier J.E. , Martin J.B. , Snyder S.H. 1984 Autoradiographic localization of somatostatin receptors in rat brain European Journal of Pharmacology 101: 307-309

Trulson M.E. , Arasteh K. 1985 Morphine increases the activity of midbrain dopamine neurons in vitro European Journal of Pharmacology 114: 105-109

Uhl G.R. , Kuhar M.J. 1984 Chronic neuroleptic treatment enhances neurotensin receptor binding in human and rat substantia nigra Nature 309: 350-352

Uhl G.R. , Snyder S.H. 1976 Regional and subcellular distributions of brain neurotensins Life Sciences 19: 1827-1832

Uhl G.R. , Hackney G.O. , Torchia M. , Stranov V. , Tourtellotte W.W. , Whitehouse P.J. , Tran V. , Strittmatter S. 1986 Parkinson's disease: nigral receptor changes support peptidergic role in nigrostriatal modulation Annals of Neurology 20: 194-203

Uhl G.R. , Whitehouse P.J. , Price D.L. , Tourtelotte W.W. , Kuhar M.J. 1984 Parkinson's disease: depletion of substantia nigra neurotensin receptors Brain Research 308: 186-190

Van Dijk A. , Richards J.G. , Trzeciak A. , Gillessen D. , Mohler H. 1984 Cholecystokinin receptors: biochemical demonstration and autoradiographical localization in rat brain and pancreas using [3H]cholecystokinin as radioligand Journal of Neuroscience 4: 1021-1033

Vecsei L. , Kiraly C. , Bollok I. , Nagy A. , Varga J. , Penke B. , Telegdy G. 1984 Comparative studies with somatostatin and cysteamine in different behavioral tests on rats Pharmacology, Biochemistry and Behaviour 21: 833-837

Verhoeven W M A , van Ree J.M. 1987 Antipsychotic properties of neuroleptic-like neuropeptides in schizophrenia: a clinical review Human Psychopharmacology 2: 137-149

Vincent S. , Hokfelt T. , Christensson I. , Terenius L. 1982 Immunohistochemical evidence for a dynorphin immunoreactive striato-nigral pathway European Journal of Pharmacology 85: 251-252

Voigt M.M. , Wang R.Y. 1984 In vivo release of dopamine in the nucleus accumbens of the rat: modulation by cholecystokinin Brain Research 296: 189-194

Voigt M. , Wang R.Y. , Westfall T.C. 1986 Cholecystokinin octapeptides alter the release of endogenous dopamine from the rat nucleus accumbens in vitro Journal of Pharmacology and Experimental Therapeutics 237: 147-153

Voorn P. , Roest G. , Groenewegen H.J. 1987 Increase of enkephalin and decrease of substance P immunoreactivity in the dorsal and ventral striatum of the rat after midbrain 6-hydroxydopamine lesions Brain Research 412: 391-396

Wachi M. , Okuda M. , Togashi S. , Miyashita O. , Wakahoi T. 1987 Effects of methamphetamine administration on brain neurotensin-like immunoreactivity in rats Neuroscience Letters 78: 222-226

Waldmeier P.C. , Kam R. , Stocklin K. 1978 Increased dopamine metabolism in rat striatum after infusions of substance P into the substantia nigra Brain Research 159: 223-227

Walker J.M. , Thompson L.A. , Frascella J. , Friederich M.W. 1987 Opposite effects of μ and κ opiates on the firing-rate of dopamine cells in the substantia nigra of the rat European Journal of Pharmacology 134: 53-59

Wand P. , Kuschinsky K. , Sontag K-H. 1973 Morphine-induced muscular rigidity in rats European Journal of Pharmacology 24: 189-193

Wang R.Y. , Hu X-T. 1986 Does cholecystokinin potentiate dopamine action in the nucleus accumbens? Brain Research 380: 363-367

Waters C.M. , Hunt S.P. , Jenner P. , Marsden C.D. 1987a Localization of neurotensin receptors in the forebrain of the common marmoset and the effects of treatment with the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Brain Research 412: 244-253

Waters C.M. , Hunt S.P. , Jenner P. , Marsden C.D. 1987b An immunohistochemical study of the acute and long-time effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the marmoset Neuroscience 23: 1025-1039

White F.J. , Wang R.Y. 1984 Interactions of cholecystokinin octapeptide and dopamine on nucleus accumbens neurons Brain Research 300: 161-166

Widerlov E. , Wilts C.D. , Mailman R.B. , Nemeroff C.B. , McCown T.J. , Prange A.J. , Breese G.R. 1982a Increase in dopamine metabolism in rat brain by neurotensin Journal of Pharmacology and Experimental Therapeutics 223: 1-6

Widerlov E. , Lmdstrom L.H. , Besev G. , Manberg P. , Nemeroff C.B. , Breese G.R. , Kizer J.S. , Prange A.J. 1982b Subnormal CSF levels of neurotensin in a subgroup of schizophrenic patients: normalization after neuroleptic treatment American Journal of Psychiatry 139: 1122-1126

Wood P.L. , Stotland M. , Richard J.W. , Rackham A. 1980 Actions of mu, kappa, sigma, delta and agonist/antagonist opiates on striatal dopaminergic function Journal of Pharmacology and Experimental Therapeutics 215: 697-703

Worms P. , Martinez J. , Briet C. , Castro B. , Biziere K. 1986 Evidence for dopaminomimetic effect of intrastriatally injected cholecystokinin octapeptide in mice European Journal of Pharmacology 121: 395-401

Yokoo H. , Nakahara T. , Matsumoto T. , Inanaga K. , Uchimura H. 1987 Effect of TRH analog (DN-1417) on tyrosine hydroxylase activity in mesocortical, mesolimbic and nigrostriatal dopaminergic neurons of rat brain Peptides 8: 49-53

Young W.S. III , Kuhar M.J. 1981 Neurotensin receptor localization by light microscopic autoradiography in rat brain Brain Research 206: 273-285

Zamir N. , Skofitsch G. , Bannon M.J. , Helke C.J. , Kopin I.J. , Jacobowitz D.M. 1984 Primate model of Parkinson's disease: alterations in multiple opioid systems in the basal ganglia Brain Research 322: 356-360

Zarbin M.A. , Innis R.B. , Wamsley J.K. , Snyder S.H. , Kuhar M.J. 1983 Autoradiographic localization of cholecystokinin receptors in rodent brain Journal of Neuroscience 3: 877-906

Zetler G. 1985 Antistereotypic effects of cholecystokinin octapeptide (CCK-8), ceruletide and related peptides on apomorphine-induced gnawing in sensitized mice Neuropharmacology 24: 251-259