Psilocybin-assisted psychotherapy for dying cancer patients – aiding the final trip

Abdallah CG Adams TG Kelmendi B . (2016) Ketamine’s mechanism of action: A path to rapid-acting antidepressants. Depress Anxiety 33: 689–697.

Akechi T Okuyama T Onishi J . (2008) Psychotherapy for depression among incurable cancer patients. Cochrane Database Syst Rev 16: CD005537.

Amoroso T Workman M (2016) Treating posttraumatic stress disorder with MDMA-assisted psychotherapy: A preliminary meta-analysis and comparison to prolonged exposure therapy. J Psychopharmacol 30: 595–600.

Belser AB Agin-Liebes F Swift TC . (in press) Patient experiences of psilocybin-assisted psychotherapy: An interpretative phenomenological analysis. Journal of Humanistic Psychology.

Breitbart W Rosenfeld B Pessin H . (2015) Meaning-centered group psychotherapy: An effective intervention for improving psychological well-being in patients with advanced cancer. J Clin Oncol 33: 749–754.

Chochinov HM Kristjanson LJ Breitbart W . (2011) Effect of dignity therapy on distress and end-of-life experience in terminally ill patients: A randomised controlled trial. Lancet Oncol 12: 753–762.

Classen C Butler LD Koopman C . (2001) Supportive-expressive group therapy and distress in patients with metastatic breast cancer: A randomized clinical intervention trial. Arch Gen Psychiatry 58: 494–501.

Duman RS Aghajanian GK Sanacora G . (2016) Synaptic plasticity and depression: New insights from stress and rapid-acting antidepressants. Nat Med 22: 238–249.

Feder A Parides MK Murrough JW . (2014) Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: A randomized clinical trial. JAMA Psychiatry 71:681–688.

Goodwin PJ Leszcz M Ennis M . (2001) The effect of group psychosocial support on survival in metastatic breast cancer. N Engl J Med 345: 1719–1726.

Griffiths RR Johnson MW Carducci MA . (2016) Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. J Psychopharmacol 30: 1181-1197.

Institute of Medicine (2007) Treatment of PTSD: An Assessment of the Evidence. Washington DC: Institute of Medicine, National Academy of Sciences.

Jiang H White MP Greicius MD . (2016) Brain activity and functional connectivity associated with hypnosis. Cereb Cortex. Epub ahead of print 28 July 2016. DOI: 10.1093/cercor/bhw220.

Kierkegaard S (1941) The Sickness Unto Death. Princeton, NJ: Princeton University Press, p. 9.

Kissane DW Grabsch B Clarke DM . (2007) Supportive-expressive group therapy for women with metastatic breast cancer: Survival and psychosocial outcome from a randomized controlled trial. Psychooncology 16: 277–286.

Leiner AS Kearns MC Jackson JL . (2012) Avoidant coping and treatment outcome in rape-related posttraumatic stress disorder. J Consult Clin Psychol 80: 317–321.

McNair PM Lorr M Droppleman LF (1981) Manual for the Profile of Mood States. 2nd edn. San Diego: Educational and Industrial Testing Service.

Mithoefer MC Grob CS Brewerton TD (2016) Novel psychopharmacological therapies for psychiatric disorders: Psilocybin and MDMA. Lancet Psychiatry 3: 481–488.

Nemeroff CB Heim CM Thase ME . (2003) Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma. Proc Natl Acad Sci U S A 100: 14293–14296.

Paulson S Davidson R Jha A . (2013) Becoming conscious: The science of mindfulness. Ann N Y Acad Sci 1303: 87–104.

Ross S Bossin A Guss J . (2016) Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: A randomized controlled trial. J Psychopharmacol 30: 1165-1180.

Sessa B (2016) MDMA and PTSD treatment: PTSD: From novel pathophysiology to innovative therapeutics. Neurosci Lett. Epub ahead of print 6 July 2016. doi: 10.1016/j.neulet.2016.07.004.

Spiegel D (1994) Living Beyond Limits: New Hope and Help for Facing Life-Threatening Illness. New York: Ballantine/Fawcett.

Spiegel D (2013) Tranceformations: Hypnosis in brain and body. Depress Anxiety 30: 342–352.

Spiegel D Classen C (2000) Group Therapy for Cancer Patients: A Research-Based Handbook of Psychosocial Care. New York: Basic Books.

Spiegel D Glafkides MC (1983) Effects of group confrontation with death and dying. Int J Group Psychother 33: 433–447.

Spiegel D Yalom ID (1978) A support group for dying patients. Int J Group Psychother 28: 233–245.

Spiegel D Bloom JR Yalom I (1981) Group support for patients with metastatic cancer. A randomized outcome study. Arch Gen Psychiatry 38: 527–533.

Spiegel H Spiegel D (1987) Trance and Treatment: Clinical Uses of Hypnosis. Washington, DC: American Psychiatric Press.

Temel JS Greer JA Muzikansky A . (2010) Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med 363: 733–742.