Does the Brain Noradrenaline Network Mediate the Effects of the CO2 Challenge? Reply to Reviewers' Comments

Argyropoulos S V, Bailey J E, Hood S D, Kendrick A H, Rich A S, Laszlo G, Nash J R, Lightman S, Nutt D J (2002) Inhalation of 35% CO2 results in activation of the HPA axis in healthy volunteers . Psychoneuroendocrinology 27: 715-729

Bellodi L, Caldirola D, Bertani A (2003) Does the brain noradrenaline network mediate the effects of the CO2 challenge? J Psychopharmacol 17: 263-264

Griez E, Schruers K (2003) Mechanisms of CO2 challenges . J Psychopharmacol 17: 260-262

Kaye J, Buchanan F, Kendrick A, Lightman SL (2002) The endocrinology of acute hypercapnia - a novel means of testing HP axis sensitivity . Proceedings of the American Endocrine Society, June 2002

Nutt D J (1989) Altered central a2-adrenoceptor sensitivity in panic disorder . Arch Gen Psychiatry 46: 165-169

Szabo S T, de Montigny C, Blier P (2000) Progressive attenuation of the firing of locus coeruleus noradrenaline neurons by sustained administration of SSRIs . Int J Neuropsychopharmacol 3: 1-11

Szabo T, Blier P (2001) Functional and pharmacological characterisation of the modulatory role of serotonin on the firing activity of locus coeruleus noradrenaline neurons . Brain Res 922: 9-20