Methadone: opioid,N-methyl-D-aspartate antagonist or both?

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References

Zylicz Z . Opioid responsive central pain of cerebrovascular origin: a case report. Palliat Med 1997; 11: 495–496.

Backonja M , Arndt G , Gombar KA , Check B , Zimmerman M . Response to chronic neuropathic pain syndromes to ketamine: a preliminary study. Pain 1994; 56: 51–57.

Eide PK , Stubhaug A , Stenehjem A . Central dysaesthesia pain after traumatic spinal cord injury is dependent on N-methyl-D-aspartate receptor activation. Neurosurgery 1995; 37: 1080–1087.

Wood T , Sloan R . Successful use of ketamine for central pain. Palliat Med 1997; 11: 57–58.

Ripamonti C , Zecca E , Bruera E . An update on the clinical use of methadone for cancer pain. Pain 1997; 70: 109–115.

Gorman AL , Elliott KJ , Inturrisi CE . The d- and l- isomers of methadone bind to the non-competitive site on the N-methyl-D-aspartate (NMDA) receptor in rat forebrain and spinal cord. Neurosci Lett 1997; 223: 5–8.