Clinical uncertainty and Covid-19: Embrace the questions and find solutions

Koffman J Etkind SN Gross J , et al. Uncertainty and Covid-19: how are we to respond? J R Soc Med 2020; 1–6. DOI: 10.1177/0141076820930665.

Fox RC. Training for uncertainty. In: Merton R Reader GC Kendall P (eds) The student-physician: introductory studies in the sociology of medical education. Cambridge, MA: Harvard University Press, 1957, pp. 207–241.

Mishel MH. Reconceptualization of the uncertainty in illness theory. Imag J Nurs Scholarsh 1990; 22: 256–262.

Schwarze ML Taylor LJ. Managing uncertainty – harnessing the power of scenario planning. N Engl J Med 2017; 377: 206–208.

Simpkin AL Schwartzstein RM. Tolerating uncertainty – the next medical revolution? N Engl J Med 2016; 375: 1713–1715.

Liang W Liang H Ou L , et al. Development and validation of a clinical risk score to predict the occurrence of critical illness in hospitalized patients with COVID-19. JAMA Intern Med 2020; 12: e202033.

Newport KB Malhotra S Widera E. Prognostication and proactive planning in COVID-19. J Pain Symptom Manage. Epub ahead of print 7 May 2020. DOI: 10.1016/j.jpainsymman.2020.04.152.

Gibbon LM GrayBuck KE Buck LI , et al. Development and implementation of a clinician-facing prognostic communication tool for patients with COVID-19 and critical illness. J Pain Symptom Manage. Epub ahead of print 8 May 2020. DOI: 10.1016/j.jpainsymman.2020.05.005.

Yourman LC Lee SJ Schonberg MA , et al. Prognostic indices for older adults: a systematic review. JAMA 2012; 307: 182–192.

Intensive Care Society. Clinical guidance: assessing whether COVID-19 patients will benefit from critical care, and an objective approach to capacity challenges. London: Intensive Care Society, 2020.

Swiss Academy of Medical Sciences. COVID-19 pandemic: triage for intensive-care treatment under resource scarcity. Swiss Med Wkl 2020; 150: w20229.

Ballesteros Sanz MÁ Hernández-Tejedor A Estella Á , et al. Recomendaciones de ‘hacer’ y ‘no hacer’ en el tratamiento de los pacientes críticos ante la pandemia por coronavirus causante de COVID-19 de los Grupos de Trabajo de la Sociedad Española de Medicina Intensiva, Crítica y Unidades Coronarias (SEMICYUC). Med Intensiva. Epub ahead of print 8 April 2020. DOI: 10.1016/j.medin.2020.04.001.

Maves RC Downar J Dichter JR , et al. Triage of scarce critical care resources in COVID-19: an implementation guide for regional allocation: an expert panel report of the task force for mass critical care and the American College of Chest Physicians. Chest. Epub ahead of print 11 April 2020. DOI: 10.1016/j.chest.2020.03.063.

Intensive Care National Audit & Research Centre (ICNARC). ICNARC report on COVID-19 in critical care. London: ICNARC, 2020, 32 p.

Bristowe K Carey I Hopper A , et al. Patient and carer experiences of clinical uncertainty and deterioration, in the face of limited reversibility: a comparative observational study of the AMBER care bundle. Palliat Med 2015; 29: 797–807.

Upshur REG Faith K Gibson JL , et al. Stand on guard for thee: ethical considerations in preparedness planning for pandemic influenza. Toronto, ON, Canada: University of Toronto, 2005.

Etkind SN Bristowe K Bailey K , et al. How does uncertainty shape patient experience in advanced illness? A secondary analysis of qualitative data. Palliat Med 2017; 31: 171–180.

King’s Health Partners. Life lines. London: King’s Health Partners, 2020.

Gawande A. Complications: a surgeon’s notes on an imperfect science. London: Profile Books, 2008.