To use a single fibre laser Doppler fluxmeter to assess the microcirculatory effects of compression stockings.
Design:
Controlled study comprising patient and control groups.
Setting:
Department of Surgery, University College London Medical School, London, UK.
Patients and participants:
Ten patients with lipodermatosclerosis caused by chronic venous insufficiency and 10 control subjects.
Interventions:
Measurements were made from the liposclerotic skin of patients and 8 cm above the medial malleolus in controls. Laser Doppler flux (LDF), blood ce velocity (BCV) and concentration of moving blood cells (CMBC) were recorded with the subject lying supine. A class II graduated compression stocking was applied to the leg and laser Doppler recordings were repeated. The protocol was repeated with the subject sitting.
Main outcome measures:
The effects of a compression stocking on LDF, BCV and CMBC in the horizontal and sitting positions were measured.
Results:
In patients in the supine position, the compression stocking resulted in a 28% median increase in LDF (p = 0.03), with a corresponding 29% median increase in BCV. There was no significant change in CMBC. In the sitting position, the compression stocking caused a 105% median increase in LDF (p < 0.01) due to a corresponding 89% median increase in BCV (p = 0.01); there was only 25% median increase in CMBC. The effects of compression in controls were similar to those in patients.
Conclusion:
Compression stockings may be effective in the treatment of chronic venous insufficiency by increasing the microcirculatory flow velocity.
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