Magnetic resonance imaging and P300 (event-related auditory evoked potentials) in the assessment of postoperative cerebral injury following coronary artery bypass graft surgery
Restricted accessOtherFirst published online July, 1993
Magnetic resonance imaging and P300 (event-related auditory evoked potentials) in the assessment of postoperative cerebral injury following coronary artery bypass graft surgery
Cerebral injury following coronary artery bypass grafting (CABG) surgery was investigated with magnetic resonance imaging (MRI) and P300, a long-latency endogenous evoked potential associated with psychological processing of stimulus information. Twelve patients were studied before and after surgery. Prior to surgery, MRI abnormalities were found in all but one patient. After surgery, five patients had new abnormalities, mainly deep white-matter lesions (DWML). Postoperative P300 latency was significantly increased in six patients. P300 topographical distribution showed a shift from predominantly posterior cerebral regions to frontal regions in most patients. Postoperative P300 and MRI deficits were found in three of the five patients. One of the patients with marked MRI change (DWML in caudate nucleus) did not show P300 deficit.
Get full access to this article
View all access options for this article.
References
1.
Newman S.The incidence and nature of neuropsychological morbidity following cardiac surgery. Perfusion1989; 4: 93-100.
2.
Shaw PJThe incidence and nature of neurological morbidity following cardiac surgery: a review. Perfusion1989; 4: 83-91.
3.
Smith P., Treasure T., Newman S. et al. Cerebral consequences of cardiopulmonary bypass. Lancet1986;i: 823-25.
4.
Blauth C., Arnold J., Kohner EM, Taylor KMRetinal microembolism during cardiopulmonary bypass demonstrated on retinal fluorescein angiography. Lancet1986; ii: 837-39.
5.
McConnell JR , Fleming WH, Chu WK et al. Magnetic resonance imaging of the brain in infants and children before and after cardiac surgery. Am J Dis Child1990;144:374-78.
6.
Sellman M., Hindmarsh T., Wert T., Semb Bkh.Magnetic resonance imaging of the brain before and after open heart operations . Ann Thorac Surg1992; 53: 807-12.
7.
De La Paz RL, Steinberg GK, Mitchell S. et al. MRI of cerebral injury following open heart valve replacement surgery. Abstracts of the 10th annual scientific meeting and exhibition of the Society of Magnetic Resonance in Medicine, San Francisco, August 1991, volume 1, page 335.
8.
Schmidt R., Fazekas F., Offenbacher H. et al. Results of pre and postoperative MRI in coronary artery bypass surgery (CABG). Neurology1990; 40: 324.
9.
Vik A., Brubakk AO, Rinck PA, Sande E., Levang OW, Sellevold O.MRI: a method to detect minor brain damage following coronary bypass surgery ? Neuroradiology1991; 33: 396-98.
10.
Sontaniemi KA, Sulg IA, Hokkanen TEQuantative EEG as a measure of cerebral dysfunction before and after open heart surgery. ElectroencephalClin Neurophysiol1980; 50: 81-95.
11.
Sontaniemi KA, Monohen H., Hokkanen TELong term cerebral outcome after open-heart surgery: a five year neuropsychological follow-up study. Stroke1986; 17: 410-16.
12.
Newman SP, Toner I., Peden CJ et al. Neuropsychological and MRI outcome following routine coronary artery graft surgery. Perfusion1993 (in press).
13.
Giesser BS, Schroeder MM, La Rocca NG et al. Endogenous event-related potentials as indices of dementia in multiple sclerosis patients. Electroencephal Clin Neurophysiol1992; 85: 320-29.
14.
Polich J., Ladish C., Bloom FEP300 assessment of early Alzheimer's disease. ElectroencephalClin Neurophysiol1990; 77: 179-89.
15.
Engelhardt W., Hartung E., Sold M., Silber R., Dierks T.Das akustisch evozierte Potential P300. Anaesthetist1992; 41: 717.
16.
Lehmann D., Skrandies W.Reference-free identification of components of checkerboard-evoked multichannel potential fields. ElectroencephalClin Neurophysiol1980; 48: 609-21.
17.
Fazekas F., Kleinert R., Offenbacher H. et al. The morphological correlate of incidental punctate white matter hyperintensities on MR images. AJNR1991; 12: 915-21.
18.
Graham DG, Rierley JBVascular disorders of the central nervous system. In: Adams JH, Corsellis JAN, Duchen LW eds. Neuropathology. London: Edward Arnold, 1984: 125-207.
19.
Marshall GV, Bradley WG Jr, Marshall CE, Bhoopat T., Rhodes RHDeep white matter infarction: correlation of MR imaging and histopathologic findings. Radiology1988; 167: 517-22.
20.
Moody DM, Bella MA, Chalha VR, Johnston WE, Prough DSBrain microemboli during cardiac surgery or aortography. Ann Neurol1990; 28: 477-86.
21.
Aberg T., Ronquist G., Tyden H. et al. Cerebral damage during open-heart surgery: clinical, psychometric, biochemical and CT data. Scand J Thorac Cardiovasc Surg1987; 21: 159-63.
22.
Maurer K., Riederer HH, Beckmann H.Altered P300 topography due to functional and structural disturbances in the limbic system in dementia and psychoses and to pharmacological conditions . Psychol Res1989; 29:391-93.
23.
Karniski W. , Blair RCTopographical and temporal stability of the P300. ElectorencephalClin Neurophysiol1989 ; 72: 373-83.
24.
Hillyard SA , Kutas M.Electrophysiology of cognitive processingAnn Rev Psychol1983; 34: 33-61.
25.
Halgren E., Stapleton JM, Smith M., Altafullah I.Generators of the human scalp P3 (s). In: Cracco RQ, Bodis-Wollner I eds. Evoked potentials. New York: Alan R Liss, 1986: 269-84.
26.
Smith ME, Halgren E., Sokolik M. et al. The intracranial topography of the P3 event-related potential elicited during auditory oddball. Electroencephal Clin Neurophysiol1990; 76: 235-48.
27.
Flor HPLe syndrome obsessionnel-compulsif: reflet d'un defaut de regulation fronto-caudee de l'hemisphere gauche? Encephale1990; 16: 325-29.
