Protection against hypoxic-ischaemic cerebral injury in the developing brain

Vannucci RC Experimental biology of cerebral hypoxia-ischaemia: relation to perinatal brain damage. Pediatr Res 1990; 27: 317-26.

Reynolds EO , Wyatt JS , Azzopardi D. , Edwards AD Magnetic resonance and near infrared spectroscopy for the investigation of perinatal hypoxic-ischaemic brain injury. Arch Dis Child 1989; 64: 953-63.

Roth SC , Edwards AD , Cady EB et al. Relation between cerebral oxidative metabolism following birth asphyxia and neurodevelopmental outcome and brain growth at one year. Dev Med Child Neurol 1992; 34: 285-95.

Rothman S. , Olney JW Excitotoxicity and the NMDA receptor. Trends Neurosci 1987; 10: 299-302.

Watson BD , Ginsberg MD Ischemic injury in the brain. Role of oxygen radical-mediated processes . Ann NY Acad Sci 1989; 559: 269-81.

Giulian D. , Johnson B. , Krebs JF , George JK , Tapscott M. Microglial mitogens are produced in the developing and injured mammalian brain . J Cell Biol 1991;112: 323-33.

Raff MC Social controls on cell survival and cell death. Nature 1992; 356: 397-400.

Meyer F. Calcium, neuronal hyperexcitability and ischaemic injury. Brain Res 1989; 14: 227-43.

Gunn AJ , Dragunow M. , Faull R. , Gluckman PD Effects of hypoxia-ischemia and seizures on neuronal and glial c-fos protein levels in the infant rat. Brain Res 1990; 531: 105-16.

Reynolds EO , McCormick DC , Roth SC , Edwards AD , Wyatt JS New non-invasive methods for the investigation of cerebral oxidative metabolism and haemodynamics in newborn infants. Ann Med 1991; 23: 681-86.

Driscoll M. , Chalfie M. Developmental and abnormal cell death in C. elegans. Trends Neurosci 1992; 15: 15-19.

McDonald J. , Johnston M. Physiological and pathophysiological roles of excitatory amino acids during central nervous system development . Brain Res Rev 1990; 15: 41-70.

Choi DW Glutamate neurotoxicity in cortical cell culture is calcium dependant . Neurosci Lett 1985; 58: 293-97.

Szatkowski M. , Barbour B. , Attwell D. Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake. Nature 1990; 348: 443-46.

Benveniste H. , Drejer J. , Schousboe A. , Diemer NH Elevation of the extracellular concentration of glutamate and aspartate in rat hippocampus during transient cerebral ischaemia monitored by intracerebral dialysis. J Neurochem 1984; 43: 1369-74.

Ikonomidou C. , Price JL , Mosinger JL et al. Hypobaric-ischaemic conditions produce glutamate like cytopathology in infant rat brains. J Neurosci 1989; 9: 1693-1700.

LeBlanc MH , Vibha V. , Smith B. , Parker CC , Evans OB , Smith EE MK-801 does not protect against hypoxic-ischemic brain injury in piglets . Stroke 1991; 22: 1270-75.

Cherici G. , Alesiani M. , Pellegrini-Giampietro DE , Moroni F. Ischemia does not induce the release of excitotoxic amino acids from the hippocampus of newborn rats. Dev Brain Res 1991; 60: 235-40.

Buchan A. , Pulsinelli WA Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia. J Neurosci 1990; 10: 311-16.

Miller RJ The revenge of the kianate receptor. Trends Neurosci 1992; 14: 477-79.

Wozniak DF , Olney JW , Kettinger L. , Price M. , Miller JP Behavioral effects of MK-801 in the rat. Psychopharmacology [Berl] 1990; 101: 47-56.

Traystman RJ , Kirsch JR , Koehler RC Oxygen radical mechanisms of brain injury following ischaemia and reperfusion . J Appl Physiol 1972; 71: 1185-95.

McCord JM Oxygen derived free radicals in postischaemic tissue injury. N Engl J Med 1985; 312: 159-63.

Patt A. , Horesh IR , Berger EM , Harken AH , Repine JE Iron depletion or chelation reduces ischemia/reperfusion-induced edema in gerbil brains. J Pediatr Surg 1990; 25: 224-27.

Palmer C. , Vannucci RC , Towfighi J. Reduction of perinatal hypoxic-ischemic brain damage with allopurinol . Pediatr Res 1990; 27: 332-36.

Frewen TC , Kissoon N. , Kronick J. et al. Cerebral blood flow, cross-brain oxygen extraction, and fontanelle pressure after hypoxic-ischemic injury in newborn infants. J Pediatr 1991; 118: 265-71. 27 Wyatt JS , Cope M. , Delpy DT et al. Quantitation of cerebral blood volume in newborn infants by near infrared spectroscopy . J Appl Physiol 1990; 68: 1086-91.

Ennis SR , Keep RF , Schielke GP , Betz AL Decrease in perfusion of cerebral capillaries during incomplete ischemia and reperfusion. J Cereb Blood Flow Metab 1990 ; 10: 213-20.

Dragunow M. , Sirimanne E. , Lawlor PA , Williams CE , Leah J. , Gluckman PD A role for calcitonin-gene-related peptide during recovery from hypoxic-ischaemic brain injury in the infant rat. Brain Res 1992 (in press).

Araki T. , Kogure K. , Nishioka K. Comparative neuroprotective effects of pentobarbital, vinpocetine, flunarizine and ifenprodil on ischemic neuronal damage in the gerbil hippocampus . Res Exp Med 1990; 190: 19-23.

Gunn AJ , Mydlar T. , Bennet L. et al. The neuroprotective actions of a calcium channel antagonist, flunarizine, in the infant rat. Pediatr Res 1989;25:573-76.

Jacewicz M. , Brint S. , Tanabe J. , Pulsinelli WA Continuous nimodipine treatment attenuates cortical infarction in rats subjected to 24 hours of focal cerebral ischemia . J Cereb Blood Flow Metab 1990; 10: 89-96.

Findlay JM , MacDonald RL , Weir BK Current concepts of pathophysiology and management of cerebral vasospasm following subarachnoid haemorrhage. Cerebrovasc Brain Metab Rev 1991; 3: 336-61.

Levene MI , Gibson NA , Fenton AC , Papathoma E. , Barnett D. The use of a calcium channel blocker, nicardipine, for severely asphyxiated newborn infants. Dev Med Child Neurol 1990 ; 32: 567-74.

Gluckman PD , Klempt ND , Guan J. et al. A role for IGF-I in the rescue of CNS neurons following hypoxic-ischemic injury. Biochem Biophys Res Commun 1992; 182: 593-99.

Cheng B. , Mattson MP IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage. J Neurosci 1992; 12: 1558-66.

Giulian D. , Robertson C. Inhibition of mononuclear phagocytes reduces ischemic injury in the spinal cord. Ann Neurol 1990; 27: 33-42.

Mori E. , Del Zoppo GJ , Chambers JD , Copeland BR , Arfors KE Inhibition of polymorphonuclear leukocyte adherence suppresses no-reflow after focal cerebral ischemia in baboons. Stroke 1992; 23: 712-18.

Shiga Y. , Onodera H. , Kogure K. et al. Neutrophil as a mediator of ischemic edema formation in the brain. Neurosci Lett 1991; 125: 110-12.

Gehrmann J. , Bonnekoh P. , Miyazawa T. , Hossmann KA , Kreutzberg GW Immunocytochemical study of an early microglial activation in ischaemia. J Cereb Blood Flow Metab 1992; 12: 257-69.

Merrill JE , Zimmerman RP Natural and induced cytotoxicity of obligodendrocytes by microglia is inhibitable by TGF beta. GLIA 1991; 4: 327-31. 42 Piani D. , Frei K. , Do KQ , Cuenod M. , Fontana A. Murine brain macrophages induce NMDA mediated neurotoxicity in vitro by secreting glutamate. Neurosci Lett 1991; 133: 159-62.

Janowsky JS , Finlay BL The outcome of perinatal brain damage: the role of normal neuron loss and axon retraction. Dev Med Child Neurol 1986; 28: 375-89.