A new model of in vitro cardioplegic oxygenation was evaluated by placing Ringer's infusion bags in a pressure resistant barrel filled with pure oxygen maintaining 380mmHg. In this hyperbaric environment, oxygen gradually diffused directly through the wall of the infusion bag reaching a concentration exceeding four volumes percent after 96 hours. Decay in oxygen content was less than 1.5% after one week refrigerated at 4°C. In conclusion, the method described above offers an alternative approach to cardioplegic oxygenation, with the advantage of being safe, simple and without any extra expenditure.
Get full access to this article
View all access options for this article.
References
1.
Bodenhamer RM , DeBoer Lwv, Geffin GA et al. Enhanced myocardial protection during ischemic arrest. J Thorac Cardiovasc Surg1983; 85: 769-80.
2.
Coetzee A., Kotzé J., Louw Honns J, Lochner A.Effect of oxygenated crystalloid cardioplegia on the functional and metabolic recovery of the isolated perfused rat heart. J Thorac Cardiovasc Surg1986; 91: 259-69.
3.
Ledingham Sjm , Braimbridge MV, Hearse DJImproved myocardial protection by oxygenation of the St Thomas' Hospital cardioplegic solutions. J Thorac Cardiovasc Surg1988; 95: 103-11.
Gayton RA, Dorsey Lma, Craver JM et al. Improved myocardial recovery after cardioplegic arrest with an oxygenated crystalloid solution. J Thorac Cardiovasc Surg1985; 89: 877-87.
8.
Engelman RM, Rousou JH, Lameshow S., Dobbs WAThe metabolic consequences of blood and crystalloid cardioplegia. Circulation1981; 64: 67-74.
