An arterial line filter (Swank High Flow 6000) was used during extracorporeal circulation (ECC) in 21 of 45 patients undergoing coronary artery bypass grafting, to study haematological effects. The mean age was 60 (41-69) years. All patients had obstructions of at least three coronary artery branches. Average ECC and aortic crossclamp times, drainage via chest tubes until the first day after surgery, total transfusions of blood products and haemolysis did not differ in the two groups. After 90 minutes of ECC, leukocyte counts were significantly lower in the filter group whereas haematocrit, counts of erythrocytes, lymphocytes and platelets, platelet volume, fibrinogen concentration and fibrinopeptide A were similar. Release of β-thromboglobulin and platelet factor 4 were significantly higher in the filter group. No clinically significant adverse haematological effects were observed with use of the arterial line filter, although there were indications of more pronounced platelet damage in the filter group.
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