Intraoperative anti-A/B immunoadsorption (ABO-IA) was recently introduced for ABO-incompatible (ABOi) heart transplantation. Here we report the first case of a patient transplanted with ABO-IA, that was of an age and weight that required two ABO-IA columns run in parallel, to enable the reduction in antibody titres to a sufficiently low level in the time available during implantation of the donor organ.
RobertsonAIssittRCrookR, et al.A novel method for ABO-incompatible heart transplantation. J Heart Lung Transplant2018; 37(4): 451.
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IssittRCrookRShawM, et al.The Great Ormond Street Hospital immunoadsorption method for ABO-incompatible heart transplantation: a practical technique. Perfusion2021; 36(1): 34.
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IssittRBoothJCrookR, et al.Intraoperative anti-A/B immunoadsorption is associated with significantly reduced blood product utilization with similar outcomes in pediatric ABO-incompatible heart transplantation. J Heart Lung Transplant2021; 40(11): 1433–1442.
