Restricted accessCase reportFirst published online 2020-11
Heart-lung transplantation for refractory diffuse alveolar hemorrhage supported by prolonged extracorporeal membrane oxygenation after cardiogenic shock from ST segment elevation myocardial infarction: a case report
Diffuse alveolar hemorrhage after percutaneous coronary intervention is a rare but fatal complication. Although timely application of extracorporeal membrane oxygenator and discontinuation of antiplatelet/anticoagulation is the treatment of choice, bleeding is often irreversible. Herein, we introduce a patient with refractory diffuse alveolar hemorrhage after prolonged extracorporeal membrane oxygenator and percutaneous coronary intervention, who was eventually rescued with heart-lung transplantation.
GillDSNgKNgKS.Massive pulmonary haemorrhage complicating the treatment of acute coronary syndrome. Heart2004; 90: e15.
2.
ConleyMPatinoGRomickB, et al. Abciximab-induced alveolar hemorrhage after percutaneous coronary intervention. Can J Cardiol2008; 24: 149–151.
3.
MikkilineniHBruhlSRColyerWRJr, et al. A retrospective analysis and case series of glycoprotein IIb/IIIa inhibitor associated diffuse alveolar hemorrhage: two case reports. Cases J2009; 2: 8553.
4.
IlhanEGuvencTSGuzelburcO, et al. A fatal complication of tirofiban in an octogenarian: diffuse alveolar hemorrhage. J Cardiol Cases2010; 2: e48–e51.
5.
IshidaRNomuraTKojimaA, et al. Pulmonary hemorrhage in a middle-aged woman as a complication of treatments for acute myocardial infarction. J Cardiol Cases2010; 1: e37–e41.
6.
IkedaMTanakaHSadamatsuK.Diffuse alveolar hemorrhage as a complication of dual antiplatelet therapy for acute coronary syndrome. Cardiovasc Revasc Med2011; 12: 407–411.
7.
KimYLimJLimJ, et al. Pulmonary alveolar hemorrhage after clopidogrel use for ST elevation myocardial infarction. Korean Circ J2013; 43: 497–499.
8.
RyuHJJungYSKimMH, et al. A case of diffuse alveolar hemorrhage following abciximab therapy. Korean J Med2013; 84: 562–566.
9.
WhitmoreTJO'SheaJPStaracD, et al. A case of pulmonary hemorrhage due to drug-induced pneumonitis secondary to ticagrelor therapy. Chest2014; 145: 639–641.
10.
ParasuramanSKTeoAIMillarCG, et al. Pneumonitis and pulmonary haemorrhage after acute myocardial infarction. Clin Med2015; 15: 591–593.
11.
YildirimFKaraIOkuyanH, et al. Diffuse alveolar hemorrhage associated with low molecular weight heparin and dual anti-platelet therapy after percutaneous coronary intervention. Clin Respir J2017; 11: 1071–1073.
12.
GrondahlB.Pulmonary alveolar hemorrhage while on dual antiplatelet therapy. Clin Med Rev Case Rep2016; 3: 118.
13.
OualimSElhardaCABenzeroualD, et al. Pulmonary alveolar hemorrhage mimicking a pneumopathy: a rare complication of dual antiplatelet therapy for ST elevation myocardial infarction. Pan Afr Med J2016; 24: 308.
14.
KahyaogluMGecmenCGunerA, et al. A rare complication: diffuse alveolar haemorrhage following acute coronary syndrome. Kardiol Pol2017; 75: 507.
15.
YilmazSKilicOYaylaliYT.Diffuse alveolar hemorrhage associated with ticagrelor therapy after percutaneous coronary intervention. Anatol J Cardiol2018; 20: 60–61.
16.
IoachimescuOCStollerJK. Diffuse alveolar hemorrhage: diagnosing it and finding the cause. Cleve Clin J Med2008; 75: 258, 260, 264–255.
17.
ValgimigliMBuenoHByrneRA, et al. 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS: the task force for dual antiplatelet therapy in coronary artery disease of the European Society of Cardiology (ESC) and of the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J2018; 39: 213–260.
18.
LevineGNBatesERBittlJA, et al. 2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines: an update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention, 2011 ACCF/AHA guideline for coronary artery bypass graft surgery, 2012 ACC/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease, 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction, 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes, and 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery. Circulation2016; 134: e123–e155.
KhushKKCherikhWSChambersDC, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-fifth adult heart transplantation report-2018; focus theme: multiorgan transplantation. J Heart Lung Transplant2018; 37: 1155–1168.
