In this manuscript, we present the first experience of evaluating donation after circulatory death (DCD) lungs, using the normothermic preservation Organ Care System (OCS) and subsequent successful transplantation. The OCS could be a useful tool for the evaluation of marginal lungs from DCD donors as it allows a proper recruitment and bronchoscopy in such donations in addition to continuous ex-vivo perfusion and assessment and treatment during transport. The OCS could potentially be a standard of care in the evaluation of marginal lungs from DCD.
WarneckeGMoradiellosJTudoracheI. Normothermic perfusion of donor lungs for preservation and assessment with the Organ Care System Lung before bilateral transplantation: a pilot study of 12 patients. Lancet2012; 380: 1851–1858.
2.
SteenSIngemanssonRBudrikisABolysRRoscherRSjöbergT. Successful transplantation of lungs topically cooled in the non-heart-beating donor for 6 hours. Ann Thorac Surg1997; 63: 345–351.
3.
SteenSSjöbergTPierreLLiaoQErikssonLAlgotssonL. Transplantation of lungs from a non-heart-beating donor. Lancet2001; 357: 825–829.
4.
Van De WauwerCVerschuurenEAvan der BijW. The use of non-heart-beating lung donors category III can increase the donor pool. Eur J Cardiothorac Surg2011; 39: e175–180.
MorrisseyPEMonacoAP. Donation after circulatory death: current practices, ongoing challenges, and potential improvements. Transplantation2014; 97: 258–264.
7.
PereraMT. The super-rapid technique in Maastricht category III donors: has it developed enough for marginal liver grafts from donors after cardiac death?Curr Opin Organ Transplant2012; 17: 131–136.
8.
Van RaemdonckDERegaFRNeyrinckAPJannisNVerledenGMLerutTE. Non-heart-beating donors. Semin Thorac Cardiovasc Surg2004; 16: 309–321.
9.
SnellGIOtoTLevveyB. Evaluation of techniques for lung transplantation following donation after cardiac death. Ann Thorac Surg2006; 81: 2014–2019.
10.
SnellGILevveyBJWilliamsTJ. Non-heart beating organ donation. Intern Med J2004; 34: 501–503.
11.
SnellGIGriffithsAMacfarlaneL. Maximizing thoracic organ transplant opportunities: the importance of efficient coordination. J Heart Lung Transplant2000; 19: 401–407.
12.
DarkJ. Personal communication. 2007.
13.
SnellGLevveyBOtoT. Effect of multiorgan donation after cardiac death retrieval on lung performance. Aust New Zealand J Surg2008; 78: 262–265.
