This paper provides an overview of activities and initiatives under way in Botswana that aim to improve the provision and management of information in the health sector. Many of these initiatives are based on the use of ICTs. The paper considers the role that ICT plays in ensuring that health information is provided to health workers and consumers in support of the three health related Millennium Development Goals (reducing child mortality; improving maternal health; and combating HIV/AIDS and malaria). The paper outlines these initiatives and considers whether there is more that needs to be done to ensure that health information is well managed and reaches those it should reach, at the right time and in the right form.