In addition to clinical criteria, self-perceptions of vision-related functioning and well-being are recognized as important measures for characterizing the disability associated with visual impairment. This report assessed the impact of visual impairment in a subset of the African-origin participants of the population-based Barbados Eye Studies, using the US National Eye Institute's 25-item Visual Functioning Questionnaire (NEI-VFQ-25). Visual impairment was associated with significantly (P ≤ 0.01) lower VFQ scores in multidimensional aspects of vision-related quality of life (QOL), including vision-related activities and psychosocial functioning. Adjusted mean composite scores were 12 points (95% confidence interval: 9.5, 14.5) and 31 points (26.7, 34.6) lower for low vision and blindness, respectively, compared with no impairment, and 13 points (7.7, 17.6) lower for visual impairment not correctable, compared with correctable with refraction. In this population with high rates of visual disability, impaired visual acuity adversely impacted the self-perceived QOL, as measured by this instrument.
Broman, A.T., Munoz, B., West, S.K., Rodriguez, J., Sanchez, R., Snyder, R. & Klein, R. (2001) `Psychometric Properties of the 25-Item NEU-VFQ in a Hispanic Population: Proyecto VER', Investigative Ophthalmology & Visual Science42: 606-13.
2.
Broman, A.T., Munoz, B., Rodriguez, J., Sanchez, R., Quigley, H.A., Klein, R., Snyder, R. & West, S.K. (2002) `The Impact of Visual Impairment and Eye Disease on Vision-Related Quality of Life in a Mexican-American Population: Proyecto VER', Investigative Ophthalmology & Visual Science43: 3393-8.
3.
Chia, E.M., Mitchell, P., Rochtchina, E., Foran, S. & Wang, J.J. (2003) `Unilateral Visual Impairment and Health Related Quality of Life: The Blue Mountains Eye Study', British Journal of Ophthalmology87: 392-5.
4.
Chia, E.M., Wang, J.J., Rochtchina, E., Smith, W., Cumming, R.R. & Mitchell, P. (2004) `Impact of Bilateral Visual Impairment on Health-Related Quality of Life: The Blue Mountains Eye Study', Investigative Ophthalmology & Visual Science45: 71-6.
5.
Chia, E.M., Mitchell, P., Ojaimi, E., Rochtchina, E. & Wang, J.J. (2006) `Assessment of Vision-Related Quality of Life in an Older Population Subsample: The Blue Mountains Eye Study', Ophthalmic Epidemiology13: 371-7.
6.
Chylack, L.T. JR., Leske, M.C., Mccarthy, D., Khu, P., Kashiwagi, T. & Sperduto, R. (1989) `Lens Opacities Classification System II (LOCS II)', Archives of Ophthalmology107: 991-7.
7.
Clemons, T.E., Chew, E.Y., Bressler, S.B. & Mcbee, W., FOR The Areds Research Group (2003 ) `National Eye Institute Visual Function Questionnaire in the Age-Related Eye Disease Study (AREDS)' (AREDS report no. 10), Archives of Ophthalmology121: 211-7.
8.
Globe, D., Varma, R., Azen, S.P., Paz, S., Yu, E., Preston-Martin, S. & The Los Angeles Latino Eye Study Group (2003) `Psychometric Performance of the NEI VFQ-25 in Visually Normal Latinos: The Los Angeles Latino Eye Study', Investigative Ophthalmology & Visual Science44: 1470-8.
9.
Hyman, L., Wu, S. Y., Connell, A. M. S., Schachat, A., Nemesure, B., Hennis, A., Leske, M. C. & The Barbados Eye Study Group (2001) `Prevalence and Causes of Visual Impairment in the Barbados Eye Study', Ophthalmology108: 1751-6.
10.
Hyman, L.G., Komaroff, E., Heijl, A., Bengtsson, B. & Leske, M.C., FOR The Early Manifest Glaucoma Trial Group (2005) `Treatment and Vision-Related Quality of Life in the Early Manifest Glaucoma Trial', Ophthalmology112: 1505-13.
11.
Klein, R., Moss, S.E., Klein, B.E., Gutierrez, P. & Mangione, C.M. (2001) `The NEI-VFQ 25 in People with Long-Term Type 1 Diabetes Mellitus: The Wisconsin Epidemiologic Study of Diabetic Retinopathy', Archives of Ophthalmology119: 733-40.
12.
Leske, M. C., Connell, A. M. S., Schachat, A. P., Hyman, L. & The Barbados Eye Studies Group (1994) `The Barbados Eye Study: Prevalence of Open Angle Glaucoma', Archives of Ophthalmology112: 821-9.
13.
Leske, M. C., Connell, A. M. S., Wu, S. Y., Nemesure, B., Hennis, A., Schachat, A. & Li, X., For The Barbados Eye Studies Group (2001) `Incidence of Open-Angle Glaucoma', Archives of Ophthalmology119: 89-95.
14.
Leske, M. C., Wu, S. Y., Hyman, L., Nemesure, B., Hennis, A. & Schachat, A., For The Barbados Eye Studies Group ( 2004a) `Four-Year Incidence of Visual Impairment: Barbados Incidence Study of Eye Diseases', Ophthalmology111: 118-24.
15.
Leske, M. C., Wu, S. Y., Nemesure, B., Yang, L. & Hennis, A., For The Barbados Eye Studies Group (2004b) `9-Year Incidence of Lens Opacities in the Barbados Eye Studies', Ophthalmology111: 483-90.
16.
Mangione, C.M., Lee, P.P., Gutierrez, P.R., Spritzer, K., Berry, S. & Hays, R.D., FOR The National Eye Institute Visual Function Questionnaire Field Test Investigators (2001) `Development of the 25-item National Eye Institute Visual Function Questionnaire', Archives of Ophthalmology119: 1050-8.
17.
Nirmalan, P.K.,Tielsch, J.M., Katz, J., Thulasiraj, R.D., Krishnadas, R., Ramakrishnan, R. & Robin, A.L. (2005) `Relationship between Vision Impairment and Eye Disease to Vision-Specific Quality of Life and Function in Rural India: The Aravind Comprehensive Eye Survey', Investigative Ophthalmology & Visual Science46: 2308-12.
18.
Nutheti, R., Shamanna, B.R., Nirmalan, P.K., Keefe, J.E., Krishnaiah, S., Rao, G.N. & Thomas, R. (2006) `Impact of Impaired Vision and Eye Disease on Quality of Life in Andhra Pradesh', Investigative Ophthalmology & Visual Science47: 4742-8.
19.
Scott, I.U., Smiddy, W.E., Schiffman, J., Feuer, W.J. & Pappas, C.J. (1999) `Quality of Life of Low-Vision Patients and the Impact of Low-Vision Services', American Journal of Ophthalmology128: 54-62.
20.
The Eye Diseases Prevalence Research Group ( 2004) `Causes and Prevalence of Visual Impairment among Adults in the United States', Archives of Ophthalmology122: 477-85.
21.
Thylefors, B., Négrel, A.D., Pararajasegaram, R. & Dadzie, K.Y. (1995) `Global Data on Blindness', Bulletin of the World Health Organization73: 115-21.
22.
Varma, R., Wu, J., Chong, K., Azen, S. P., Hays, R. D. & Los Angeles Latino Eye Study Group (2006) `Impact of Severity and Bilaterality of Visual Impairment on Health-Related Quality of Life', Ophthalmology113: 1846-53.
23.
Vu, H.T.V., Keeffe, J.E., Mccarty, C.A. & Taylor, H.R. (2005) `Impact of Unilateral and Bilateral Vision Loss on Quality of Life', British Journal of Ophthalmology89: 360-3.
24.
Weih, L.M., Hassell, J.B. & Keeffe, J. (2002) `Assessment of the Impact of Vision Impairment' , Investigative Ophthalmology & Visual Science43: 927-35.
25.
West, S.K., Munoz, B., Rubin, G.S., Schein, O.D., Bandeen-Roche, K., Zeger, S., German, P.S., Fried, L.P. & The See Project Team (1997 ) `Function and Visual Impairment in a Population-Based Study of Older Adults. The SEE Project', Investigative Ophthalmology & Visual Science38: 72-82.
26.
West, S. K., Rubin, G. S., Broman, A. T., Munoz, B., Bandeen-Roche, K. & Turano, K., For The See Project Team (2002) `How does Visual Impairment Affect Performance on Tasks of Everyday Life? The SEE Project', Archives of Ophthalmology120: 774-80.
