Abstract
The adsorption of farmorubicine, methotrexate and 5-fluorouracil on adsorbents based on polyethylene grafted with polyacrylic acid (polyacrylate content Δp of 4, 15 and 80%) and polyacrylamide (polyacrylamide content Δp of 14%) has been investigated. A comparative estimation of the sorptive activity of the investigated adsorbents with respect to different antitumour compounds has been carried out. The influence of NaCl addition on the parameters of the kinetics and equilibrium adsorption of farmorubicine and methotrexate has been established.
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References
1.
Al-Achi
A.
Borovjerdi
M.
(1990 ) Drug Dev. Ind. Pharm. 16 , 1325 .
2.
Alykov
N.M.
Nekrest'janova
T.V.
Jakovleva
L.V.
(1991 ) Zh. Anal. Chim. 46 , 1642 .
3.
Czejka
M.
Shuller
J.
(1992 ) Arch. Pharm. (Paris) 325 , 69 .
4.
Czejka
M.
Shuller
J.
Fogl
U.
(1992 ) Arch. Pharm. (Paris) 325 , 73 .
5.
Hickman
J.A.
Beere
H.M.
Wood
A.C.
Waters
C.M.
Parmar
R.
(1992 ) Toxicol. Lett. 64/65 , 553 .
6.
Kovbuz
M.A.
Felitsyn
N.M.
Dmitrenko
A.V.
(1994 ) Colloid J . 56 , 127 .
7.
Luk'janova
O.N.
Pisarev
O.A.
Muravjova
T.D.
Katrucha
G.S.
Samsonov
G.V.
(1991 ) Zh. Prikl. Khim. 64 , 1361 .
8.
Neurnberg
B.
Kohlbrenner
M.
Faulkner
R.
Furst
O.E.
(1989 ) J. Chromatogr. Biomed. Appl. 487 , 476 .
9.
Pushkarev
B.S.
(1974 ) Poluchenie, structura i svoistva sorbentov , Nauka , Moscow .
10.
Quebbeman
E.J.
Hoffman
N.E.
Hamid
A.A.R.
Ausman
R.K.
(1984 ) J. Liq. Chromatogr. 7 , 1489 .
11.
Samsonov
G.V.
Pisarev
O.A.
Luk'janova
O.N.
Muravjova
T.D.
(1991a ) Zh. Prikl. Khim. 64 , 1239 .
12.
Samsonov
G.V.
Pisarev
O.A.
Muravjova
T.D.
Nasledov
D.G.
Komogorova
T.A.
(1991b ) Dokl. Akad. Nauk. SSSR 319 , 408 .
13.
Stewart
M.J.
Farid
Y.Y.Z.
Watson
I.D.
(1982 ) Anal. Proc. 19 , 179 .
14.
Tjaden
H.R.
Lingeman
H.
Reuwijk
H.J.E.
de Bruijn
E.A.
Keizer
H.Y.
van der Greef
J.
(1988 ) Chromatographia 25 , 806 .
15.
Yoshida
Sh.
Adashi
T.
Hirose
Sh.
(1988 ) J. Chromatogr. Biomed. Appl. 430 , 156 .
16.
Yurtov
E.V.
Vinetskaya
E.G.
(1990 ) Int. Solv. Extr. Conf. (ISEC ′90). Kyoto , Abstr. 288.