Abstract
Samples of a newly synthesised class of macromolecular compound, poly(N-allyl acrylamide)s, obtained by thermal condensation at 200°C of a polyelectrolyte complex, polyfallylammonium acrylate), were tested for both cytotoxicity and water absorption. The cytotoxicity tests (Level I), carried out on both an unmodified complex and a fully condensed polyamide, indicate that these materials exert no acute toxicity on 3T3 fibroblast cells. The water absorption tests, carried out on both partially condensed and fully condensed polyamides, at three different pH values, indicate that these materials are suitable to be used for the controlled delivery of drugs containing ionic or polar groups.
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