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References
1.Home Office . Non-technical summaries . London : Home Office . Available at : https://www.gov.uk/government/publications/non-technical-summaries-granted-in-2018 (2020, accessed 3 September 2020) .
2.
Beale
A
. What are the Three Rs? Nottingham : FRAME . Available at : https://frame.org.uk/2018/07/16/what-are-the-three-rs/ (2018, accessed 3 September 2020) .
3.EMA . ICH guideline M3(R2) on non-clinical safety studies for the conduct of human clinical trials and marketing authorisation for pharmaceuticals . London : European Medicines Agency . Available at : https://www.ema.europa.eu/en/documents/scientific-guideline/ich-guideline-m3r2-non-clinical-safety-studies-conduct-human-clinical-trials-marketing-authorisation_en.pdf (2009, accessed 3 September 2020) .
4.EMA . Reflection paper providing an overview of the current regulatory testing requirements for medicinal products for human use and opportunities for implementation of the 3Rs . London : European Medicines Agency . Available at : https://www.ema.europa.eu/en/documents/scientific-guideline/reflection-paper-providing-overview-current-regulatory-testing-requirements-medicinal-products-human_en.pdf (2018, accessed 3 September 2020) .
5.
Beale
A
. Alzheimer’s research: A ‘mighty mouse’ is still a mouse . Nottingham : FRAME . Available at : https://frame.org.uk/2019/09/25/alzheimers-research/ (2019, accessed 3 September 2020) .
6.Home Office . Annual statistics of scientific procedures on living animals, Great Britain 2019. HC512 . London : The Stationery Office , 2020 , 28 pp.
