The Alliance is an exciting new collaboration, founded to address an urgent need to drive research and development, policymaking, awareness, outreach, and education into human-based methods of safety testing and biomedical research
Get full access to this article
View all access options for this article.
References
1.
SuntharalingamG., PerryM.R., WardS., BrettS.J., Castello-CortesA., BrunnerM.D., & PanoskaltsisN. (2006). Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. New England Journal of Medicine355, 1018–1028.
2.
MooreN. (2016). Lessons from the fatal French study BIA 10 2474. British Medical Journal353, i2727.
3.
WaringJ., ArrowsmithJ., LeachA.R., LeesonP.D., MandrellS., OwenR.M., PairaudeauG., PennieW.D., PickettS.D., WangJ., WallaceO., & WeirA. (2015). An analysis of the attrition of drug candidates from four major pharmaceutical companies. Nature Reviews Drug Discovery14, 475–486.
4.
GodleeF. (2014). How predictive and productive is animal research?British Medical Journal, 348, g3719.
5.
National Research Council (2007). Toxicity Testing in the 21st Century: A Vision and a Strategy, 216 pp. Washington, DC, USA: The National Academies Press.
