Much worthy effort on the Three Rs is under way in the UK, but its promise of a reduction in laboratory animal use will only be credible and laudable when the number of procedures and animals are progressively and permanently reduced
BallsM., GoldbergA.M., FentemJ.H., BroadheadC.L., BurchR.L., FestingM.F.W., FrazierJ.M., HendriksenC.F.M., JenningsM., van der KampM.D.O., MortonD.B., RowanA.N., RussellC., RussellW.M.S., SpielmannH., StephensM.L., StokesW.S., StraughanD.W., YagerJ.D., ZurloJ. & van ZutphenB.F.M. (1995). The Three Rs: The way forward. The report and recommendations of ECVAM Workshop 11. ATLA23, 838–866.
Hudson-ShoreM. (2014). Annual Statistics of Scientific Procedures on Living Animals 2013: Experimentation continues to rise — the reliance on genetically-altered animals must be addressed. ATLA42, 261–266.
9.
CombesR.D. & BallsM. (2014). Every silver lining has a cloud: The scientific and animal welfare issues surrounding a new approach to the production of transgenic animals. ATLA42, 137–145.