Lower organisms can be particularly useful as high discrimination models in fundamental research, but cannot offer the high fidelity required when specific questions are asked about humans in health and disease, and about their responses to drugs and other chemicals
Get full access to this article
View all access options for this article.
References
1.
RussellW.M.S. & BurchR.L. (1959). The Principles of Humane Experimental Technique, xiv + 238pp. London, UK: Methuen.
2.
BallsM. (2013). The wisdom of Russell and Burch. 3. Fidelity and discrimination. ATLA41, P12–P13.
3.
HubrechtR.C. (2014). The Welfare of Animals Used in Research, vii + 271pp. Chichester, West Sussex, UK: Wiley Blackwell.
