The freedom of choice of the experimenter is often very much wider than it at first appears. The full use of this freedom is the mark alike of humane and successful experimentation. There is, perhaps, no limit in animal experimentation to the progress of refinement
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References
1.
RussellW.M.S., & BurchR.L. (1959). The Principles of Humane Experimental Technique. xiv + 238 pp. London, UK: Methuen.