Exemplification of the Implementation of Alternatives to Experimental Testing in Chemical Risk Assessment — Case Studies from the CADASTER Project

European Parliament (2006). Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. Official Journal of the European Union L396, 30.12.2006, 1–849.

Bradbury S.P. , Feijtel T.C. , & Van Leeuwen C.J. (2004). Meeting the scientific needs of ecological risk assessment in a regulatory context. Environmental Science & Technology 38, 463A–470A.

Van Leeuwen C.J. , Bro-Rasmussen F. , Feijtel T.C. , Arndt R. , Bussian B.M. , Calamari D. , Glynn P. , Grandy N.J. , Hansen B. , Van Hemmen J.J. , Hurst P. , King N. , Koch R. , Muller M. , Solbe J.F. , Speijers G.A. , & Vermeire T. (1996). Risk assessment and management of new and existing chemicals. Environmental Toxicology & Pharmacology 2, 243–299.

Durjava M.K. , Kolar B. , Arnus L. , Papa E. , Kovarich S. , Sahlin U. , & Peijnenburg W. (2013). Experimental assessment of the environmental fate and effects of triazoles and benzotriazoles. ATLA 41, 65–75.

Brandmaier S. , Novotarskyi S. , Sushko I. , & Tetko I.V. (2013). From descriptors to predicted properties: Experimental design using the applicability domain estimation. ATLA 41, 33–47.

Cassani S. , Kovarich S. , Papa E. , Roy P. , Rahmberg M. , Nilsson S. , Sahlin U. , Jeliazkova N. , Kochev N. , Pukalov O. , Tetko I.V. , Brandmaier S. , Durjava M.K. , Kolar B. , Peijnenburg W.J.G.M. , & Gramatica P. (2013). Evaluation of CADASTER QSAR models for aquatic toxicity of (benzo)triazoles and prioritisation by consensus. ATLA 41, 49–64.

Rorije E. , Aldenberg T. , & Peijnenburg W. (2013). Read-across estimates of aquatic toxicity for selected fragrances. ATLA 41, 77–90.

Sahlin U. , Golsteijn L. , Iqbal M.S. , & Peijnenburg W. (2013). Arguments for considering QSAR uncertainty in hazard and risk assessments. ATLA 41, 91–110.

Sahlin U. (2013). Uncertainty in QSAR predictions. ATLA 41, 111–125.

Aldenberg T. , & Rorije E. (2013). Species sensitivity distribution estimation from uncertain (QSAR-based) effects data. ATLA 41, 19–31.

Tetko I.V. , Sopasakis P. , Kunwar P. , Brandmaier S. , Novotarskyi S. , Charochkina L. , Prokopenko V. , & Peijnenburg W.J.G.M. (2013). Prioritisation of polybrominated diphenyl ethers (PBDEs) by using the QSPR-THESAURUS web tool. ATLA 41, 127–135.