Special Anniversary Volume — Issue 4: Replacement — Focus on the Development of Therapeutics

Gard T. & Clothworthy M. (eds) (2009). Proceedings of the Speed and Safety in Drug Discovery Symposium. ATLA 37, Suppl. 1, 65 pp.

Russell W.M.S. & Burch R.L. (1959). The Principles of Humane Experimental Technique, 238 pp. London, UK: Methuen.

Bhogal N. (2009). 21st century drug development: advances, opportunities and challenges. ATLA 37, 335–339.

Pereira S.P. , Pereira G.C. , Moreno A.J. & Oliveira P.J. (2009). Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions? ATLA 37, 355–365.

Smith R.A. (2009). Twenty-first century challenges for in vitro neurotoxicity. ATLA 37, 367–375.

Li A.P. (2009). The use of the Integrated Discrete Multiple Organ Co-culture (IdMOC^®) system for the evaluation of multiple organ toxicity. ATLA 37, 377–385.

Corsini E. & Roggen E.L. (2009). Immunotoxicology: opportunities for non-animal test development. ATLA 37, 387–397.

Coleman R.A. (2009). Drug discovery and development tomorrow — changing the mindset. ATLA 37, Suppl. 1, 1–4.

Higbee R.G. , Byers A.M. , Dhir V. , Drake D. , Fahlenkamp H.G. , Gangur J. , Kachurin A. , Kachurina O. , Leistritz D. , Ma Y. , Mehta R. , Mishkin E. , Moser J. , Mosquera L. , Nguyen M. , Parkhill R. , Pawar S. , Poisson L. , Sanchez-Schmitz G. , Schanen B. , Singh I. , Song H. , Tapia T. , Warren W. & Wittman V. (2009). An immunologic model for rapid vaccine assessment — a clinical trial in a test tube. ATLA 37, Suppl. 1, 19–27.

Tsaioun K. & Jacewicz M. (2009). De-risking drug discovery with ADDME — avoiding drug development mistakes early. ATLA 37, Suppl. 1, 47–55.

Seymour M. (2009). The best model for humans is human — how to accelerate early drug development safely. ATLA 37, Suppl. 1, 61–65.

SCHER (2009). The Need for Non-human Primates in Biomedical Research, Production and Testing of Products and Devices, 38 pp. Brussels, Belgium: Scientific Committee on Health and Environmental Risks, European Commission, Health & Consumer Protection DG. Available at: http://ec.europa.eu/health/ph_risk/committees/04_scher/docs/scher_o_110.pdf (Accessed 24.08.09).

Bailey J. & Taylor K. (2009). The SCHER report on non-human primate research — biased and deeply flawed. ATLA 37, 427–435.

Anon. (2009). Statistics of Scientific Procedures on Living Animals, Great Britain 2008, 477 pp. HC 800. Norwich, UK: The Stationery Office.

Gill V. (2009). Upward jump in lab animal tests. BBC Online, 21 July 2009. Available at: http://news.bbc.co.uk/1/hi/sci/tech/8161253.stm (Accessed 21.07.09).