3.7. Genotoxicity and Mutagenicity

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Torous D.K. , Hall N.E. , Murante F.G. , Gleason S.E. , Tometsko C.R. , & Dertinger S.D. (2003). Comparative scoring of micronucleated reticulocytes in rat peripheral blood by flow cytometry and microscopy. Toxicological Sciences 74, 309–314.

Evans H.J. (1976). Cytological methods for detecting chemical mutagens. In Chemical Mutagens, Principles and Methods for their Detection (ed. Hollaender A. ), Vol. 4, pp. 1–29. New York, USA, and London, UK: Plenum Press.

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Ames B. , Lee F.D. , & Durston W.E. (1973). An improved bacterial test system for the detection and classification of mutagens and carcinogens. Proceeding of the National Academy of Sciences of the USA 70, 782–786.

Ames B.N. , Mccann J. , & Yamasaki E. (1975). Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity Test. Mutation Research 31, 347–364.

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Sorenson W.G. , Simpson J.P. , & Ong T.M. (1981). Comparison of mutagenic and recombinogenic effects of some adenine analogues in Saccharomyces cerevisiae D7. Mutation Research 82, 95–100.

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Zimmermann F.K. , von Borstel R.C. , von Halle E.S. , Parry J.M. , Siebert D. , Zetterberg G. , Barale R. , & Loprieno N. (1984). Testing of chemicals for genetic activity with Saccharomyces cerevisiae: a report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutation Research 133, 199–244.

Chu E.H.Y. , & Malling H.V. (1968). Mammalian Cell Genetics. II. Chemical Induction of Specific Locus Mutations in Chinese Hamster Cells In vitro. Proceedings of the National Academy of Sciences of the USA 61, 1306–1312.

Clive D. , Flamm W.G. , Machesko M.R. , & Bernheim N.J. (1972). A mutational assay system using the thymidine kinase locus in mouse lymphoma cells. Mutation Research 16(7), 77–87.

Aaron C.S. , Bolcsfoldi G. , Glatt H.R. , Moore M. , Nishi Y. , Stankowski L. , Theiss J. , & Thompson E. (1994). Mammalian Cell Gene Mutation Assays Working Group Report. Report of the International Workshop on Standardisation of Genotoxicity Test Procedures. Mutation Research 312, 235–239.

Aaron C.S. , & Stankowski L.F. Jr. (1989). Comparison of the AS52/XPRT and the CHO/HPRT assays: Evaluation of six drug candidates. Mutation Research 223, 121–128.

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Moore M.M. , De Marini D.M. , DeSerres F.J. , & Tindall K.R. eds (1987). Banbury Report 28: Mammalian Cell Mutagenesis. New York, USA: Cold Spring Harbor Laboratory.

Moore M.M. , Harrington-Brock K. , Doerr C.L. , & Dearfield K.L. (1989). Differential mutant quantitation at the mouse lymphoma TK and CHO HGPRT loci. Mutagenesis 4, 394–403.

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Tice R.R. , Agurell E. , Anderson D. , Burlinson B. , Hartmann A. , Kobayashi H. , Miyamae Y. , Rojas E. , Ryu J.C. , & Sasaki Y.F. (2000). The single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing. Environmental and Molecular Mutagenesis 35, 206–221.

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Ostiling O. , & Johanson K.J. (1987). Microelectrophoretic study of radiation-induced DNA damage in individual cells. Biochemical and Biophysical Research Communications 123, 291–298.

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Kukkelhoven M.W.A.C. (1985). Covalent binding of benzo(a)pyrene metabolites to DNA of cultured human hair follicle keratinocytes. Archives of Toxicology 57, 6–12.

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Kuroki T. , Hosomi J. , Chida K. , Hosoi J. , & Nemoto N. (1987). Inter-individual variation of arylhydrocarbon-hydroxylase activity in cultured epidermal and dermal cells. Japanese Journal of Cancer Research 78, 45–53.

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Corton J.C. , & Stauber A.J. (2000). Toward construction of a transcript profile database predictive of chemical toxicity. Toxicological Sciences 58, 217–219.

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Holmes E.W. , Nicholson J.K. , & Tranter G. (2001). Metabonomic characterisation of genetic variation in toxicological and metabolic responses using probabilistic neural networks. Chemical Research in Toxicology 14, 182–191.

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Pennie W.A. (2000). Use of cDNA microarray to probe and understand the toxicological consequences of altered gene expression. Toxicology Letters 112/113, 473–477.

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Criswell K.A. , Krishna G. , Zielinski D. , Urda G.A. , Juneau P. , Bulera S. , & Bleavins M.R. (2003). Validation of a flow cytometric acridine orange micronuclei methodology in rats. Mutation Research 528, 1–18.

Dertinger S.D. , Chen Y. , Miller R.K. , Brewer K.J. , Smudzin T. , Torous D.K. , Hall N.E. , Olvany K.A. , Murante F.G. , & Tometsko C.R. (2003). Micro-nucleated CD71-positive reticulocytes: a blood-based endpoint of cytogenetic damage in humans. Mutation Research 542, 77–87.

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