3.5. Skin Absorption and Penetration

SCCNFP (2003). The Scientific Committee on Cosmetic Products and Non-Food Products Opinion Concerning Basic Criteria for the In Vitro Assessment of Dermal Absorption of Cosmetic Ingredients. Updated October 2003 (SCCNFP/0750/03), 9 pp. Brussels, Belgium: DG SANCO/C/2, European Commission.

OECD (2004). OECD Guidelines for the Testing of Chemicals No. 427: Skin Absorption: in vivo method, 8 pp. Paris, France: Organization for Economic Cooperation and Development.

OECD (2004). OECD Guidelines for the Testing of Chemicals No. 428: Skin Absorption: in vitro method, 8 pp. Paris, France: Organization for Economic Cooperation and Development.

OECD (2004). Guidance Document for the Conduct of Skin Absorption Studies. OECD Environmental Health and Safety Publications, Series on Testing and Assessment No. 28, 31 pp. Paris, France: Environment Directorate, Organization for Economic Cooperation and Development.

Diembeck W. , Beck H. , Benech-Kieffer F. , Courtellemont P. , Dupuis J. , Lovell W. , Paye M. , Spengler J. , & Steiling W. (1999). Test guidelines for in vitro assessment of dermal absorption and percutaneous penetration of cosmetic ingredients. Food and Chemical Toxicology 37, 191–205.

COLIPA (1995). Cosmetic Ingredients: Guidelines for Percutaneous Absorption/Penetration, 36 pp. Brussels, Belgium: COLIPA.

European Commission (2003). Technical Guidance Document on Risk Assessment in support of Commission Directive 93/67/EEC on Risk Assessment for new notified substances, Commission Regulation (EC) No. 1488/94 on Risk Assessment for existing substances and Directive 98/8/EC of the European Parliament and of the Council concerning the placing of biocidal products on the market. Doc. EUR 20418 EN/1. Brussels, Belgium: European Commission.

ECETOC (1993). Monograph No. 20: Percutaneous absorption, 83 pp. Brussels, Belgium: European Centre for Ecotoxicology and Toxicology of Chemicals.

Environmental Protection Agency (1999). Proposed rule for in vitro dermal absorption rate testing of certain chemicals of interest to occupational safety and health administration. Federal Register 64, 31074–31090.

Howes D. , Guy R. , Hadgraft J. , Heylings J. , Hoeck U. , Kemper F. , Maibach H. , Marty J-P. , Merk H. , Parra J. , Rekkas D. , Rondelli I. , Schaefer H. , Täuber U. , & Verbiese N. (1996). Methods for assessing percutaneous absorption. The report and recommendations of ECVAM workshop 13. ATLA 24, 81–106.

Ross J.H. , Dong M.H. , & Krieger R.I. (2000). Conservatism in pesticide exposure assessment. Regulatory Toxicology and Pharmacology 31, 53–58.

Anon. (2002). Guidance Document on Dermal Absorption (Sanco/222/2000 rev. 6 of 27 November 2002), 15 pp. Brussels, Belgium: DG SANCO/C/2, European Commission.

SCCNFP (1999). Basic Criteria for the in vitro assessment of percutaneous absorption of cosmetic ingredients, adopted by the SCCNFP during the 8th plenary meeting of 23 June 1999 (SCCNFP/0167/99 Final). Brussels, Belgium: DG SANCO/C/2, European Commission. Website http://europa.eu.int/comm/health/ph_risk/committees/sccp/docshtml/sccp_out48_en.htm (Accessed 1.4.05).

SCCNFP (2000). Guidelines for in vitro methods to assess percutaneous absorption of cosmetic ingredients. In Notes of Guidance for Testing of Cosmetic Ingredients for their Safety Evaluation (SCCNFP/0321/00 Final), 114 pp. Brussels, Belgium: DG SANCO/C/2, European Commission.

SCCNFP (2003). The Scientific Committee on Cosmetic Products and Non-Food Products Intended for Consumers Notes of Guidance For Testing of Cosmetic Ingredients For Their Safety Evaluation. 5th Revision, adopted by the SCCNFP during the plenary meeting of 20 October 2003 (SCCNFP/0690/03 Final), 102 pp. Brussels, Belgium: DG SANCO/C/2, European Commission.

Schaefer H. , & Redelmeier T.E. (1996). Skin Barrier: Principles of Percutaneous Absorption, 310 pp. Basel, Switzerland: Karger AG.