HalleW. (1985). Grundlagen der Zytotoxizität in vitro und ihre Bedeutung für die toxikologische Prüfung von Antiseptika. In Handbuch der Antiseptik, Teilband I/5: Toxische und allergische Nebenwirkungen von Antiseptika. (ed. KramerA., BerencsiG., & WeuffenW.), pp. 84–112. Berlin, Germany: VEB Verlag Volk und Gesundheit.
2.
HalleW., GoeresE., & BaegerI. (1985). Besitzt die Vorhersage der LD50 mit Hilfe der Zellkultur Allgemeingueltigkeit?Pharmazie42, 848–850.
3.
HuntS.M., ChrzanowskaC., BarnettC.R., BrandH.N., & FawellJ.K. (1987). A comparison of in vitro cytotoxicity assays and their application to water samples. ATLA15, 20–29.
4.
KnoxP., UphillP.F., FryJ.R., BenfordJ., & BallsM. (1986). The FRAME multicentre project on in vitro cytotoxicology. Food and Chemical Toxicology24, 457–463.
5.
StarkD.M., ShopsisC., BorenfreundE., & BabichH. (1986). Progress and problems in evaluating and validating alternative assays in toxicology. Food and Chemical Toxicology24, 449–455.
6.
GarleM.J., HammondA.H., & FryJ.R. (1987). The cytotoxicity of 27 chemicals to V79 Chinese hamster cells. ATLA15, 30–32.
7.
ClothierR.H., HulmeL., AhmedA.B., ReevesH.L., SmithM., & BallsM. (1988). In vitro cytotoxicity of 150 chemicals to 3T3-L1 cells, assessed by the FRAME kenacid blue method. ATLA16, 84–95.
8.
LewisR.J.Sr., & TatkenR.L. eds (1982). Registry of Toxic Effects of Chemical Substances, pp. 81–116. Cincinnati, OH, USA: US Department of Health and Human Services, National Institute for Occupational Safety and Health.
9.
TatkenR.L., & LewisR.J.Sr. eds (1983). Registry of Toxic Effects of Chemical Substances, 2014 pp. Cincinnati, OH, USA: US Department of Health and Human Services, National Institute for Occupational Safety and Health.
10.
LewisR.J.Sr., & SweetD.V. eds (1984). Registry of Toxic Effects of Chemical Substances, 731 pp. Cincinnati, OH, USA: US Department of Health and Human Services, National Institute for Occupational Safety and Health.
11.
HalleW., & GoeresE. (1988). Register der Zyto-toxizität (IC50) in der Zellkultur und Moeglich-keiten zur Abschätzung der akuten Toxizität (LD50). In Beiträge zur Wirkstofforschung (ed. OehmeP., LöweH., & GoeresE.), pp. 1–108. Berlin, Germany: Institut fuer Wirkstofforschung.
12.
HalleW. (1998). Toxizitätsprüfungen in Zellkulturen für eine Vorhersage der akuten Toxizität (LD50) zur Einsparung von Tierversuchen, 93 pp. Jülich, Germany: Forschungszentrum Jülich.
13.
SpielmannH., GenschowE., LiebschM., & HalleW. (1999). Determination of the starting dose for acute oral toxicity (LD50) testing in the Up and Down Procedure (UDP) from cytotoxicity data. ATLA27, 957–966.
14.
BabichH., & BorenfreundE. (1990). Applications of the neutral red cytotoxicity assay to in vitro toxicology. ATLA18, 129–144.
15.
MummeryC.L., Van den BrinkS., van der SaagP.T., & De LaatS.W. (1983). Screening for cytotoxicity in neuroblastoma cells. I. Dependence of growth inhibition on the presence of serum. Toxicology Letters18, 201–209.
16.
HalleW., & GoeresE. (1987). Vorhersage von LD50 – Werten mit der Zellkultur. Pharmazie42, 245–248.
17.
SmithL.M., ClothierR.H., HillidgeS., & BallsM. (1992). Modification of the FRAME kenacid blue method for cytotoxicity tests on volatile materials. ATLA20, 230–234.
18.
BenfordD.J., & GoodS. (1989). Development of cytotoxicity tests for assessment of the toxicity of water samples taken from the environment. Molecular Toxicology1, 419–425.
19.
AcostaD., SorensenE.M.B., AnuforoD.C., MitchelD.B., RamoisK., SantoneK.S., & SmithM.A. (1985). An in vitro approach to the study of target organ toxicity of drugs and chemicals. In Vitro Cellular and Developmental Biology21, 495–504.
20.
GueldenM., & FingerJ. (1992). Effects of the first twenty MEIC reference chemicals on viability, glucose consumption and spontaneous contractility of primary cultured rat skeletal muscle cells. ATLA20, 222–225.
21.
Garza-OcañasL., Torres-AlanísO., & Pieñyro-LòpezA. (1990). Evaluation of the cytotoxicity of 18 compounds in six rat cell lines. ATLA17, 246–249.
22.
RomertL., JanssonT., & JenssenD. (1994). The cytotoxicity of 50 chemicals from the MEIC study determined by growth inhibition of ascites sarcoma BP8 cells: a comparison with acute toxicity data in man and rodents. Toxicology Letters71, 39–46.
23.
SpielmannH., LiebschM., KalweitS., MoldenhauerF., WirnsbergerT., HolzhütterH-G., SchneiderB., GlaserS., GernerI., PapeW.J.W., KreilingR., KrauserK., MiltenburgerH.G., SteilingW., LuepkeN.P., MüllerN., KreuzerH., MürmannP., SpenglerJ., Bertram-NeisE., SiegemundB., & WiebelF. (1996). Results of a validation study in Germany on two in vitro alternatives to the Draize eye irritation test, the HET-CAM test and the 3T3 NRU cytotoxicity test. ATLA24, 741–858.
24.
PflegerK. (1964). Toxikologische Daten. In Biochemisches Taschenbuch, Teil II (ed. RauenH.M.), pp. 654–663. Berlin, Germany: Springer-Verlag.
25.
LewisR.J.Sr. ed. (1979). Registry of Toxic Effects of Chemical Substances, 1513 pp. Cincinnati, OH, USA: US Department of Health, Education, and Welfare, National Institute for Occupational Safety and Health.
26.
SchuppanD. ed. (1986). The Contribution of Acute Toxicity Testing to the Evaluation of Pharmaceuticals, 104 pp. Berlin, Germany: Springer-Verlag.
27.
OECD (1993). Acute oral toxicity. In OECD Guidelines for the Testing of Chemicals, pp. 1–1000. Paris, France: OECD.
28.
HanschC., & LeoA. (1979). Substituent Constants for Correlation Analysis in Chemistry and Biology, 339 pp. New York, NY, USA: John Wiley & Sons.
29.
HanschC., SammesP.G., & TaylorJ.B. eds (1991). Comprehensive Medical Chemistry, Vol. 6, Cumulative Subject Index and Drug Compendium, pp. 1–991. Oxford, UK: Pergamon Press.
30.
HalleW., & SpielmannH. (1992). Two procedures for the prediction of acute toxicity (LD50) from cytotoxicity data. ATLA20, 40–49.
HalleW., & SpielmannH. (1997). Die Prädiktion der akuten Toxizität mit Hilfe von Zytotox-izitätsdaten. In Ersatz- und Ergänzungsmethoden zu Tierversuchen, Band IV, Forschung ohne Tierversuche 1996 (ed. SchoefflH., SpielmannH., & TritthartH. A.), pp. 10–19. New York, NY, USA: Springer.
34.
Anon. (1994). SPSS Trends 6.1, pp. 1–355. Chicago, IL, USA: SPSS Inc.
35.
BudavariS. ed. (1989). The Merck Index, 11th edn, 1606 pp. Rahway, NJ, USA: Merck.
36.
LoweD.A., & StilesA.R. (1973). Pesticides: nomenclature, specifications, analysis, use, and residues in foods. Bulletin of the World Health Organization49, 169–204.
37.
HalleW. (1993). On the reliability of LD50 predictions for antiseptics by cytotoxicity determination. Hygiene und Medizin8, 209–212.
38.
HalleW., LiebschM., TraueD., & SpielmannH. (1997). Reduktion der Tierzahlen bei der Einstufung von Stoffen in die EU-Toxizitätsklassen fuer akute orale Toxizität mit Hilfe von Daten aus dem Register der Zytotoxizität (RC). ALTEX14, 8–15.
39.
SeibertH., BallsM., FentemJ.H., BianchiV., ClothierR.H., DierickxP.J., EkwallB., GarleM.J., Gómez-LéchonM.J., GribaldoL., GüldenM., LiebschM., RasmussenE., RoguetR., ShrivastavaR., & WalumE. (1996). Acute toxicity testing in vitro and the classification and labelling of chemicals. The report and recommendations of ECVAM workshop 16. ATLA24, 499–510.
40.
OECD (1996). OECD Guidelines for the Testing of Chemicals No. 423: Acute Oral Toxicity — Acute Toxic Class Method, 14 pp. Paris, France: OECD.
41.
OECD (2001). OECD Guidelines for the Testing of Chemicals No. 425: Acute Oral Toxicity — Up-and-Down Procedure, 355 pp. Paris, France: OECD.
42.
OECD (1987). OECD Guidelines for the Testing of Chemicals No. 401: Acute Oral Toxicity, 7 pp. Paris, France: OECD.
43.
OECD (1992). OECD Guidelines for the Testing of Chemicals No. 420: Acute Oral Toxicity — Fixed Dose Procedure, 14 pp. Paris, France: OECD.
44.
AhneW. (1985). Untersuchungen über die Verwendung von Fischzellkulturen fuer Toxizitätsbest-immungen zur Einschränkung und Ersatz des Fischtests. Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene180, 480–504.
45.
ShrivastavaR., DelomenieC., ChevalierA., JohnG., EkwallB., WalumE., & MassinghamR. (1992). Comparison of in vivo acute lethal potency and in vitro cytotoxicity of 48 chemicals. Cell Biology and Toxicology8, 157–170.
46.
DierickxP.J. (1989). Cytotoxicity testing of 114 compounds by the determination of the protein content in HEP G2 cell cultures. Toxicology in Vitro3, 189–193.
47.
BabichH., & BorenfreundE. (1987). Structure–activity relationship (SAR) models established in vitro with the neutral red cytotoxicity assay. Toxicology in Vitro1, 3–9.
48.
BabichH., & BorenfreundE. (1988). Structure–activity relationships for diorganotins, chlorinated benzenes, and chlorinated anilines established with bluegill sunfish BF-2 cells. Fundamental and Applied Toxicology10, 295–301.
49.
BabichH., & BorenfreundE. (1987). Aquatic pollutants tested in vitro with early passage fish cells. ATLA15, 116–122.
50.
HalleW., & SpielmannH. (1994). Zur Qualität der Vorhersage der akuten Toxizität (LD50) aus der Zytotoxizität (IC50X) fuer eine Gruppe von 26 Neurotropika aufgrund der Daten des “Erweiterten Registers der Zytotoxizität”. ALTEX11, 148–153.
51.
SchmidI., & KarzelK. (1968). Untersuchungen zur pharmakologischen Charakterisierung eines permanent in vitro wachsenden Stammes von Ehrlich-Ascitestumorzellen. Arzneimittel-Forsch18, 1498–1500.
52.
EkwallB. (1993). Correlation between cytotoxicity in vitro and LD50 values. Acta Pharmacologica et Toxicologica52, Suppl. II, 80–99.
53.
FlintO.P. (1984). An in vitro assay for teratogens with cultures of rat embryo midbrain and limb bud cells. Toxicology and Applied Pharmacology76, 383–395.
54.
PrattR.M., & WillisW.D. (1985). In vitro screening assay for teratogens using growth inhibition of human embryonic cells. Proceedings of the National Academy of Sciences, USA82, 5791–5794.
55.
BoydE.M., & TaylorF.I. (1971). Toxaphene toxicity in protein-deficient rats. Toxicology and Applied Pharmacology18, 158–167.
56.
WaldenR., & SchillerC.M. (1985). Comparative toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in four (sub)strains of adult male rats. Toxicology and Applied Pharmacology77, 490–495.