The effects on the biochemistry and physiology of the human body of diets differing only in the ratio of the two major carbohydrates, starch and sugars are discussed and related to the epidemiology of coronary heart disease and diabetes. Much of the evidence for causes of disease comes originally from epidemiology, where comparison is made between groups of people where the disease is common and groups where the disease is uncommon. But final determination of cause almost always depends on the result of experiment, with animals in the laboratory or with human volunteers.
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