We report the case of a 25-year-old woman with tetralogy of Fallot who presented with chest pain and hypertension, and on further investigation, was diagnosed with a pheochromocytoma in the right adrenal gland. She underwent surgical excision of the tumor. While the simultaneous occurrence of these two diseases is extremely rare, the suspicion of a possible relationship has been raised in the past.
de la MonteSMHutchinsGMMooreGW. Peripheral neuroblastic tumors and congenital heart disease. Possible role of hypoxic states in tumor induction. Am J Pediatr Hematol Oncol1985; 7: 109–116.
2.
FolgerGMJrRobertsWCMehriziA. Cyanotic malformations of the heart with pheochromocytoma: a report of five cases. Circulation1964; 29: 750–757.
3.
ReynoldsJLGilchristTF. Congenital heart disease and pheochromocytoma. Am J Dis Child1966; 112: 251–255.
4.
KitaTImamuraTDateH. Two cases of pheochromocytoma associated with tetralogy of Fallot. Hypertens Res2003; 26: 433–437.
5.
BalakrishnanGRavikumarRRaoSBalakrishnanKR. Tetralogy of Fallot with pheochromocytoma: an unusual therapeutic challenge. Asian Cardiovasc Thorac Ann2013; 21: 464–466.
6.
CheekDBMalinekMFraillonJM. Plasma adrenaline and noradrenalin in the neonatal period, and infants with respiratory distress syndrome and placental insufficiency. Pediatrics1963; 31: 374–384.
7.
BialestockD. Hyperplasia of the adrenal medulla in hypertension of children. Arch Dis Child1961; 36: 465–465.
8.
SherwinRP. Histopathology of pheochromocytoma. Cancer1959; 12: 861–877.
