We report a rare case of mediastinal sarcoid-like reaction presenting 5 years after colon adenocarcinoma resection. The lack of clinical and biochemical features suggestive of sarcoidosis and the high 18F-fluorodeoxyglucose uptake in mediastinal adenopathy, not seen previously, led us to suspect cancer recurrence. Pathological diagnosis obtained with a thoracoscopic biopsy confirmed sarcoidosis. Mediastinal adenopathies need to be confirmed pathologically to avoid potential interpretative pitfalls leading to toxic overtreatment.
UmezuHChidaMInoueT. Sarcoidosis development during induction chemotherapy for lung cancer mimicked progressive disease. Gen Thorac Cardiovasc Surg2010; 58: 434–437.
2.
ChidaMInoueTHonmaKMurakamiK. Sarcoid-like reaction mimics progression of disease after induction chemotherapy for lung cancer. Ann Thorac Surg2010; 90: 2031–2033.
3.
InoueKGotoRShimomuraHFukudaH. FDG-PET/CT of sarcoidosis and sarcoid reactions following antineoplastic treatment. Springerplus2013; 2: 113–113.
4.
KornackerMKraemerALeoEHoAD. Occurrence of sarcoidosis subsequent to chemotherapy for non-Hodgkin’s lymphoma: report of two cases. Ann Hematol2002; 81: 103–105.
SantiniMFiorelloAMansiL. The role of technetium-99m hexakis-2-methoxyisobutyl isonitrile in the detection of neoplastic lung lesions. Eur J Cardiothorac Surg2009; 35: 325–331.
7.
TrisoliniRTinelliCCancellieriA. Transbronchial needle aspiration in sarcoidosis: yield and predictors of a positive aspirate. J Thorac Cardiovasc Surg2008; 135: 837–842.
